BACKGROUND AND PURPOSE Diabetes mellitus may impair endothelium-dependent responses in cerebral arterioles. The basilar artery dilates in response to increases in blood flow. The goal of this study was to examine effects of diabetes mellitus on "flow-mediated" and endothelium-dependent dilatation of the basilar artery. METHODS Diabetes was induced in rats with 50 mg/kg streptozotocin. Six mon...

BACKGROUND A 75 year old lady presented with acute central retinal artery occlusion and contralateral cotton wool spots. CASE PRESENTATION General physical examination and investigations led to a diagnosis of CREST syndrome; however, association of central retinal artery occlusion with CREST syndrome is not well known. While diabetes, systemic hypertension, carotid atherosclerosis and cardiac...

Objective: A case of symptomatic cervical carotid artery stenosis with persistent primitive hypoglossal artery (PPHA) treated by carotid artery stenting (CAS) with appropriate embolic protection is reported. Case Presentation: The patient was a 65-year-old male presenting with left hemiplegia. MRI revealed infarction in the right cerebral hemisphere, and cerebral angiography demonstrated stenos...

BACKGROUND Cilioretinal artery occlusion rarely results in neovascular glaucoma, especially in cases of extensive cilioretinal infarction and combined retinal vascular occlusion. CASE A 62-year-old man with diabetes mellitus and essential hypertension showed a visual acuity of counting fingers, retinal whitening temporal to the optic disc with mild dilation and tortuosity of the retinal veins...

We prospectively studied the results of carotid angiography in 45 patients with transient or nondisabling neurologic deficits caused by lacunar infarction in the internal capsule or corona radiata and demonstrated by computed tomography. An ipsilateral stenosis at the bifurcation of the internal carotid artery was found in 14 patients (31%, 95% confidence limits 18-47%), seven of whom also had ...

One-third of patients who develop internal carotid occlusion will die or have disabling cerebral symptoms. ~ The results of urgent carotid thromboendarterectomy in patients with established internal carotid occlusion were disappointing. Extracranial to intracranial bypass in symptomatic patients with internal carotid artery occlusion produced high numbers of strokes and was not of benefit. 2 At...

We prospectively studied the results of carotid angiography in 45 patients with transient or nondisabling neurologic deficits caused by lacunar infarction in the internal capsule or corona radiata and demonstrated by computed tomography. An ipsilateral stenosis at the bifurcation of the internal carotid artery was found in 14 patients (31%, 95% confidence limits 18-47%), seven of whom also had ...

Limb-shaking is a specific clinical feature of transient ischaemic attacks that has been associated with a high-grade stenosis or occlusion of the internal carotid artery. The aim of this study was to describe the clinical characteristics of limb-shaking in patients with internal carotid artery occlusion and to investigate whether patients with limb-shaking have a worse haemodynamic state of th...

PURPOSE To distinguish between acute complete unilateral cardioembolic and atherothrombotic internal carotid artery (ICA) occlusion by using duplex carotid sonography. METHODS We studied 11 patients with cardioembolic ICA occlusion (CE group), 32 patients with atherothrombotic ICA occlusion (AT group), and 25 patients with normal angiographic findings (control group). We obtained B-mode scans...