To fully involve patients in treatment decisions, physicians need to communicate future health prospects that patients will have both with and without newly diagnosed disease. These prospects depend not only on the risks patients face from the new disease but also on the risks they face from other causes. Nowhere is an understanding of these competing risks more relevant than in the care of the...

BACKGROUND Competing risks methodology allows for an event-specific analysis of the single components of composite time-to-event endpoints. A key feature of competing risks is that there are as many hazards as there are competing risks. This is not always well accounted for in the applied literature. METHODS We advocate a simulation point of view for understanding competing risks. The hazards...

Objectives Methods accounting for competing risks in time-to-event problems are becoming common in mainstream statistical analyses. Standard approaches include those based on log-rank type tests [1] and cumulative incidence regression [2]. These approaches are based on weighting competing events by the censoring distribution. The usual cumulative incidence regression uses weights based on the p...

BACKGROUND To illustrate the 10-year risks of urinary adverse events (UAEs) among men diagnosed with prostate cancer and treated with different types of therapy, accounting for the competing risk of death. METHODS Prostate cancer is the second most common malignancy among adult males in the United States. Few studies have reported the long-term post-treatment risk of UAEs and those that have,...