A new cell-trapping method for single cell analysis devices at a very rapid flow rate, is designed, fabricated and characterized by controlling shapes of microstructures and their arrangements in array just simply and effectively within the microfluidic channels. We simulated using a commercialized computational fluidic dynamic simulator (CFD-ACE+) and demonstrated experimentally that the cell-...

The intent of this study is to evaluate existing gaps in computational fluid dynamics (CFD) technology with an emphasis on hypersonic flow modeling. The importance of validation is highlighted, especially with respect to the dearth of available hypersonic flow data. Modeling challenges relevant to hypersonic air-breathing propulsion, such as multi-phase flow and turbulent mixing, are discussed ...

Single staggered is a design development of normal wire and tube heat exchanger that wires are welded with staggered configuration on two sides. Capacity of wire and tube heat exchanger is the ability of the heat exchanger to release heat. The objective of this study is to analyse the effect of wire pitch (pw) on capacity of single staggered wire and tube heat exchanger. The research...

This paper presents the analysis of duct design using static and dynamic approaches. The static approach is used to find out applicability between the design and material applied. The material used in this paper is Thermoplastic Olefins (TPO). For the dynamic approach, the focusing is only on the CFD simulations. The fatigue life in this design and material applied also covered. Keywords—CFD, s...

A three-dimensional computational fluid dynamics- (CFD-) model based on a differential pressure laminar flow bioreactor prototype was developed to further examine performance under changing culture conditions. Cell growth inside scaffolds was simulated by decreasing intrinsic permeability values and led to pressure build-up in the upper culture chamber. Pressure release by an integrated bypass ...

Dynamic Contrast Enhanced Computed Tomography is an imaging tool that aids in evaluating functional characteristics in different stages of disease assessment: diagnostic, treatment effectiveness and monitoring. At the present time, following all the technological advances, there remains no universally validated method of quantitative, non-invasive, perfusion imaging. In order to address this ch...

This paper examines the effect of various combustion models when predicting the environment in a building arising from fire in a room. The use of a stoichiometric combustion model will usually over-predict the efficiency of the combustion process in the fuel-rich areas and hence over-predict the temperature field. A modified combustion model presented in this paper can improve the predicted res...

A benchmark turbulent Backward Facing Step (BFS) airflow was studied in detail through a program of tightly coupled experimental and CFD analysis. The theoretical and experimental approaches were developed simultaneously in a “building block” approach and the results used to verify each “block”. Information from both CFD and experiment was used to develop confidence in the accuracy of each tech...

This paper illustrates a step-by-step process on how to use "The Manual for Verification, Validation, and Reporting of Indoor Environment CFD analyses" developed by ASHRAE. The details of the manual are further explained through an example of indoor environment modeling (an office with mechanical displacement ventilation). The verification, validation, and reporting do not have to be documented...