The small GTP-binding protein, Rho1/RhoA plays a central role in cytokinetic actomyosin ring (CAR) assembly and cytokinesis. Concentration of Rho proteins at the division site is a general feature of cytokinesis, yet the mechanisms for recruiting Rho to the division site for cytokinesis remain poorly understood. We find that budding yeast utilizes two mechanisms to concentrate Rho1 at the divis...

We consider the problem of maximimizing, over all choices of n nonzero elements a 1 ; : : : ; a n 2 R m , the number of the 2 n subset sums P i2I a i , over all index sets I, belonging to some speciied target set T.tigated the case m = 1 and T = f0; 1g of this problem, and showed that the maximum in their case is ? n+1 b n+1 2 c , but it remained open until now to prove the essential uniqueness...

We have investigated the ability to kneel after total knee replacement. We asked 75 patients (100 knees) at least six months after routine uncemented primary total knee replacement, to comment on and to demonstrate their ability to kneel. Differences between the perceived and actual ability to kneel were noted. In 32 knees patients stated that they could kneel without significant discomfort. In...