Motivated by the inadequacy of nonsurgical therapy in ameliorating congenital cardiac disease, surgical pioneers in the 1940s and 1950s began to develop techniques that would allow for the intracardiac repair of congenital heart disease. The fi rst operation on the open human heart under direct vision—closure of an atrial septal defect (ASD) in a 5-year-old girl—was performed at the University ...

BACKGROUND Secundum atrial septal defect (ASD) is a common congenital heart malformation that occurs as an isolated anomaly in 10% of individuals with congenital heart disease. Although some embryological pathways have been elucidated, the molecular etiologies of ASD are not fully understood. Most cases of ASD are isolated, but some individuals with ASD have a family history of this defect or o...

discussion children with congenital heart disease are at risk of acquiring gram-negative endocarditis even if they have not had other predisposing factors. case presentation in this study a ten-year-old boy with ventricular septal defect, who was not immune compromised and acquired klebsiella endocarditis is introduced. the patient had a favorable response to medical treatment and underwent a s...

supravalvar mitral ring is a rare congenital heart defect of surgical importance. the condition is characterized by an abnormal ridge of the connective tissue on the atrial side of the mitral valve. it often substantially obstructs the mitral valve inflow. we herein introduce a case of a supravalvar mitral ring in a 17-year-old male, who was admitted to our hospital with cardiac syncope. he had...

A case of congenital aneurysm of the pulmonary sinus (sinus of Valsalva) in a 7-year-old child is described. The child met a traumatic death and manifested no symptoms or definite signs of his valvular defect. The heart was of normal weight, and no other abnormalities of the heart or other organs were present. This is the first report of sinus aneurysm of the pulmonary valve. The pathogenetic i...

A continuous murmur like that of a persistent ductus arteriosus produced by a stenosed branch of a pulmonary artery with a post-stenotic dilatation is presented in the following case. Other abnormalities included a hypoplastic left lung, atrial septal defect, ventricular septal defect, and an absent left pulmonary artery. The literature on congenital heart disease contains increasing numbers of...

Background: Scimitar syndrome (SS) or congenital pulmonary venolobar syndrome is a rare anomaly, most commonly including partial pulmonary venous drainage into the inferior vena cava, right lung hypoplasia, dextroposition of the heart, and anomalous systemic arterial supply from aorta or one of its branches to the right lung. Case report: A 10-day-old female infant was referred to our hospital...

A case of congenital aneurysm of the pulmonary sinus (sinus of Valsalva) in a 7-year-old child is described. The child met a traumatic death and manifested no symptoms or definite signs of his valvular defect. The heart was of normal weight, and no other abnormalities of the heart or other organs were present. This is the first report of sinus aneurysm of the pulmonary valve. The pathogenetic i...

Is the most common congenital defect in dogs. It is a LR shunting defect resulting from failure of closure of the left sixth aortic arch. If left untreated it results in left sided congestive heart failure. Clinically animals present with a Continuous (Machinery) Murmur at the left heart base with Hyperkinetic Femoral Pulses. A systolic murmur of mitral regurgitation may also be ausculted secon...

A continuous murmur like that of a persistent ductus arteriosus produced by a stenosed branch of a pulmonary artery with a post-stenotic dilatation is presented in the following case. Other abnormalities included a hypoplastic left lung, atrial septal defect, ventricular septal defect, and an absent left pulmonary artery. The literature on congenital heart disease contains increasing numbers of...