Background and AimsWe asked if comprehensive bile acid profiling could provide insights into the physiopathology of ABCB4-mutated patients evaluated prognostic value taurine-conjugated tetrahydroxylated (tauro-THBA) in cholestasis.

a new folate-conjugated gold nanoparticle (aunp) has been designed to selectively target the folate receptor that is overexpressed on the surface of tumoral cells. for this purpose, we made 4-aminothiophenol, as a bifunctional linker to react with haucl4 in the presence of sodium borohydride and it was binded to the aunp surface through its thiol group. then, we conjugated amino-terminated nano...

UNLABELLED During cholestasis, accumulation of conjugated bile acids may occur in the liver and lead to hepatocellular damage. Inspired by our recent development of N-(11)C-methyl-glycocholic acid-that is, (11)C-cholylsarcosine-a tracer for PET of the endogenous glycine conjugate of cholic acid, we report here a radiosynthesis of N-(11)C-methyl-taurine-conjugated bile acids and biodistribution ...

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Many previous studies have reported that conjugated linoleic acid could be produced by starter culture bacteria, but the effects of the bacteria were not investigated. Moreover, there was no evidence of the conjugated linoleic acid-producing bacteria having potential health or nutritional effects related to conjugated linoleic acid, including reducing body fat. Here, we investigated the anti-ob...

this study was done to evaluate quality properties of pistacia atlantica var mutica (bene) nuts under deferent storage conditions and packaging. at the zero time, sfa and total tocopherol (tt) and total phenolic (tp) compounds were 6.8 and 725.28 and 40.1 mg per kg oil, respectively. some quality properties (peroxide value (pv), conjugated diene value (cdv) and carbonyle value (cv)) showed that...

BACKGROUND The hydrogel based system is found to be rarely reported for the delivery of hydrophobic drug due to the incompatibility of hydrophilicity of the polymer network and the hydrophobicity of drug. This problem can be solved by preparing semi-interpenetrating network of cross-linked polymer for tuning the hydrophilicity so as to entrap the hydrophobic drugs. The current study is to devel...