PURPOSE To investigate the presence of epithelial sodium channels (ENaC) in rabbit and human conjunctival epithelium and to test the effects of topical amiloride, a potassium-sparing diuretic that blocks the ENaC, on tear quantity in rabbits. METHODS Both healthy normal human and rabbit conjunctival tissues underwent immunohistochemistry staining for ENaC-α and γ subunits as well as for rever...

OBJECTIVE To evaluate primary cultures from human conjunctiva supplemented with fetal bovine serum, autologous serum, and platelet-rich autologous serum, over human amniotic membrane and lens anterior capsules. METHODS One-hundred and forty-eight human conjunctiva explants were cultured in CnT50(®) supplemented with 1, 2.5, 5 and 10% fetal bovine serum, autologous serum and platelet-rich auto...

An asymptomatic fungal cyst of a conjunctival infection was found and removed by biopsy in a young shepherdess. Histopathologic evaluations of the excised tissue specimen from the lesion of the conjunctiva demonstrated an epithelium lined cavity containing a tangled mycelial mass that was surrounded by inflammatory cells and the fungus was identified as Bipolaris spicifera. It is concluded that...

PURPOSE To compare various techniques of pterygium surgery including bare sclera, intraoperative mitomycin C application, conjunctival flap reconstruction, and conjunctival autografting technique. METHODS This study is designed to compare 4 currently used techniques in order to determine the complication and recurrence rates after pterygium exision. Included in the study were 77 eyes from 60 ...

Objectives: the aim was to compare 2 drops of either 5% chloramphenicol, 1% povidone-iodine or before cataract surgery on reducing colonisation bacterial flora in conjunctiva.Design: This a double-blind, randomised clinical trial study.Setting: Patients referred Shahid Sadoughi Hospital Yazd, Iran, for were studied.Participants: Totally 260 patients enrolled.Intervention: The affected lower for...

Background/aim: Povidone-iodine (PI, Betadine) is routinely used as a preoperative topical antiseptic in cataract surgery as it has been shown to reduce the incidence of postoperative endophthalmitis. However, the concentration used clinically is variable. In vitro studies have shown that PI is paradoxically more effective at lower concentration. This study was undertaken to determine if this e...

clinically misdiagnosed as choroidal melanoma. Currently, most subretinal tumors assumed to be choroidal melanomas are treated with radiotherapy without histological confirmation. The diagnosis of an RPE carcinoma may therefore be missed. Finger et al described a darkly pigmented subretinal tumor accompanied by inflammation that was suspected of being an adenocarcinoma of the RPE. In several pu...

BACKGROUND/AIM Povidone-iodine (PI, Betadine) is routinely used as a preoperative topical antiseptic in cataract surgery as it has been shown to reduce the incidence of postoperative endophthalmitis. However, the concentration used clinically is variable. In vitro studies have shown that PI is paradoxically more effective at lower concentration. This study was undertaken to determine if this ef...