Neurodegenerative disorders such as Parkinson’s disease, motor neuron disease and Alzheimer’s disease is characterized by loss of specific cells within certain regions of the brain. One of the most compelling questions is to determine why specific cell populations are vulnerable to neurodegeneration. We addressed this question by studying global gene expression changes using an animal model of ...

Neurodegenerative disorders such as Parkinson’s disease, motor neuron disease and Alzheimer’s disease is characterized by loss of specific cells within certain regions of the brain. One of the most compelling questions is to determine why specific cell populations are vulnerable to neurodegeneration. We addressed this question by studying global gene expression changes using an animal model of ...

phosphatidate phosphohydrolase (pap) from cytosolic fraction of rat liver was purified to homogeneity having specific activity of 5.14 u/mg protein. an activity staining procedure was developed to determine molecular weight of the enzyme on polyacrylamide gel electrophoresis using ferguson plot. molecular weight (m.w.) of the active pap was 298 kda. sds-page analysis showed a m.w. of 47 kda for...

introduction: currently, developing new antibacterial drugs as alternative antibiotics is a very active area of research, due to widspreading widespread prevalence of resistant strains of microorganisms. this work intends to investigate of antibacterial properties and influence on immune blood cells of the silver-based compound hexamethylenetetramine (methenamine) silver nitrate with general fo...