BACKGROUND Most corneal damage induced by contact lenses is due to interference with corneal oxygenation. OBJECTIVE To investigate the effect on the rabbit cornea of a rigid gas-permeable contact lens with a newly designed periphery. METHOD We fitted New Zealand white rabbits (n = 12) with RGP contact lenses that were identical in all respects except for the design of the periphery. In each...

BACKGROUND Visual outcome following repair of post-traumatic corneal perforation may not be optimal due to presence of irregular keratometric astigmatism. We performed a study to evaluate and compare rigid gas permeable contact lens and spectacles in visual rehabilitation following perforating corneal injuries. METHOD Eyes that had undergone repair for corneal perforating injuries with or wit...

PURPOSE To compare and analyze changes in vision quality, subjective symptoms, and psycho-social satisfaction in keratoconus and myopic patients following the wearing of contact lenses. METHODS This study enrolled 25 keratoconus and 25 myopic patients with corrected vision over 0.8 according to the Snellen chart due to treatment with contact lenses. Patients were surveyed prior to the wearing...

PURPOSE To evaluate the effect of soft contact lens type on the in vivo tear film surface quality (TFSQ) on daily disposable lenses and to establish whether two recently developed techniques for noninvasive measurement of TFSQ can distinguish between different contact lens types. METHODS Thirteen subjects wearing four different types of daily soft contact lenses participated in the study. Dyn...

Keratitis, inflammation of the cornea, can result in partial or total loss of vision and can result from infectious agents (e.g., microbes including bacteria, fungi, amebae, and viruses) or from noninfectious causes (e.g., eye trauma, chemical exposure, and ultraviolet exposure). Contact lens wear is the major risk factor for microbial keratitis; outbreaks of Fusarium and Acanthamoeba keratitis...

PURPOSE To study the effects of long-term contact lens wear on morphologic and physiologic properties of corneal endothelial cells. METHODS The endothelial permeability to fluorescein and the rate of corneal deswelling from hypoxia-induced edema were measured in 20 long-term (mean, 17+/-9 years; range, 5-33 years) contact lens wearers and 20 age-matched control subjects. From these data, the ...

BACKGROUND To assess the reproducibility of ophthalmodynamometric measurements using a new, Goldmann contact lens associated, device allowing biomicroscopic visualisation of the optic disc. METHODS The prospective clinical study included 87 eyes of 58 subjects presenting with a normal fundus (n=40), or ocular diseases (n=47). With topical anaesthesia, a Goldmann contact lens, fitted with a pr...

More than 125 million people wear contact lenses worldwide, and contact lens use is the single greatest risk factor for developing microbial keratitis. We tested the antibacterial activity of multipurpose contact lens solutions and their individual component preservatives against the two most common pathogens causing bacterial keratitis, Pseudomonas aeruginosa and Staphylococcus aureus The in v...

OBJECTIVES Starting in mid-2005, an increase in fungal keratitis caused by Fusarium spp was observed among contact lens wearers in Hong Kong, Singapore, and the USA. The objective of this study was to describe the outbreak and to determine any association with the use of Bausch & Lomb (B&L) ReNu contact lens solution. METHODS We defined a case as a disposable contact lens user with ophthalmol...