Goal-directed, coordinated movements in humans emerge from a variety of constraints that range from 'high-level' cognitive strategies based on perception of the task to 'low-level' neuromuscular-skeletal factors such as differential contributions to coordination from flexor and extensor muscles. There has been a tendency in the literature to dichotomize these sources of constraint, favouring on...

CD43, a large highly glycosylated molecule, is arguably the most abundant molecule on the surface of T cells. Nevertheless, the function of CD43 remains unclear. Utilizing fluorescence microscopy, we find that CD43 is excluded from the T cell-APC contact site. This exclusion is Ag dependent since optimal CD43 exclusion requires Ag-pulsed APC, and since signaling through CD3, in the absence of a...

Livestock diseases constitute a great threat to protein availability in Nigeria. It is thus necessary eramine how much farmers know about some deadly prevalent their stock as it would afford the farmer timely re-adjustment prevent foreseeable losses. The focus of this study was determine farmers' level awareness African Swine Fever (ASF) Agege Area Lagos State, Primary data were collected with ...

In the process of neuronal wiring, axons derived from the same functional group typically extend together, resulting in fascicle formation. How these axons communicate with one another remains largely unknown. Here, we show that protocadherin-17 (Pcdh17) supports this group extension by recruiting actin polymerization regulators to interaxonal contact sites. Pcdh17 is expressed by a subset of a...

A study is presented which assesses agricultural production in a Purchase Land area over a seven-year period and tries to identify certain socio-psychological and other variables which might be acting as constraints on farming behavior in terms of change. A survey was conducted of the whole population of 198 resident farm families; it included six questionnaires. Subjects covered included agric...