BACKGROUND Continuous beta-agonist therapy, typically in the form of inhaled albuterol, is the first line therapy for the treatment of acute and severe bronchospasm in children. Although this treatment is commonly used, concerns about cardiotoxicity have been raised. We aimed to investigate the cardiotoxic effects of continuous beta-agonist therapy in children. METHODS We conducted a retrospe...

in this paper, we introduce and characterize fuzzy wea-kly $e$-closed functions in fuzzy topological spaces and the relationship between these mappings and some properties of them are investigated.

The Beta Distribution is almost exclusively used for situations, after range normalization, wherein a continuous random variable is defined on the closed range [0, 1]. Since the beta distribution is intrinsically a two parameter distribution, this creates problems in some applications where specification of more than one parameter is difficult. In this note, two new classes of single parameter ...

Contra-rotating propellers have renewed interest from the naval architecture community, because of the recent development of electric propulsion drives and podded propulsors. Contrarotating propulsion systems have the hydrodynamic advantages of recovering part of the slipstream rotational energy which would otherwise be lost utilizing a conventional screw propeller system. The application of th...

OBJECTIVES The purpose of this experimental study was first to compare the in vivo intrinsic activity of imipenem and cefepime administered as a continuous infusion and to determine their lowest effective serum steady-state concentration (LESSC). Secondly, we studied the effect of combining therapy with tobramycin. METHODS In a Pseudomonas aeruginosa (ATCC 27853) rabbit endocarditis model, be...

The most important pharmacodynamic parameter for beta-lactam antibiotics has been shown to be the time above the MIC, which is used as an argument to administer beta-lactam antibiotics by continuous infusion. Studies in vitro and in laboratory animals comparing efficacy of continuous and intermittent infusion of beta-lactam antibiotics generally show continuous infusion to be more efficacious. ...

A low-cost bimetallic bifunctional 5-5 wt% FeNi/H-Beta-300 catalyst was investigated in solventless hydrodeoxygenation of lignin-derived model compounds isoeugenol or dihydroeugenol the batch and continuous mode. The characterized...

Transcription factors are important gene regulators with distinctive roles in development, cell signaling and cell cycling, and they have been associated with many diseases. The ConTra v3 web server allows easy visualization and exploration of predicted transcription factor binding sites (TFBSs) in any genomic region surrounding coding or non-coding genes. In this updated version, with a comple...

Because the establishment of pregnancy begins at the uterine horn ipsilateral to the corpus luteum (ipsi-horn) in cattle, levels of progesterone (P4) and receptor expression in the endometrial tissue, which regulate the intrauterine environment for embryo development, may differ between the ipsi-horn and the uterine horn contralateral to corpus luteum (contra-horn). The aim of the present study...

OBJECTIVE To compare the effects of continuous 17-beta estradiol-only silastic implants with those of continuous 17-beta estradiol plus continuous nomegestrol acetate silastic implants on symptom control, lipid profile and tolerability in postmenopausal women. METHODS This was an open-label, parallel-group study. Women with and without uterus and no contraindications to hormone therapy (HT) i...