The focus in relation to the consequences of nerve damage in diabetes has been the loss of sensation in the feet predisposing to the development of foot ulceration and lower extremity amputation (1). However, the cornea is 300– 600 times more sensitive than skin (2). In addition to serving a protective function, corneal nerves regulate corneal epithelial integrity, proliferation, and wound heal...

purpose : to report the complications and acute and chronic managements of a case of corneal bee sting injury and to report the outcome of visual performance case report : a 28-year-old caucasian man who was stung by insect and was complaining of ocular pain and decreased vision in the left eye, presented to the emergency room. a sting was found and completely removed. corneal edema, bullous ke...

BACKGROUND & OBJECTIVE Infective keratitis is rare in the absence of predisposing factors. The pattern of risk factors predisposing to infective keratitis varies with geographical regions and also influences the type of infection that occurs. The present study was aimed to identify the specific risk factors that predispose the infective keratitis (non viral) and to determine the association bet...

since alkaline substances can rapidly penetrate into the cornea and subsequently damage limbal stem cells, another source of stem cells may be necessary to reconstruct the ocular surface. omentum has some such characteristics like ability to regenerate tissue as well as anti-inflammatory capacity. presence of adult stem cells and pluripotent embryonic cell markers make it suitable in wound heal...

PURPOSE Bevacizumab is a potent recombinant humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF). The purpose of this study was to evaluate the therapeutic effect of subconjunctival injection of bevacizumab on corneal neovascularization (NV) in different rabbit models. METHODS Several rabbit models of corneal NV were used, including (1) a corneal micropocke...

PURPOSE Previous studies have suggested that the disappearance of anterior keratocytes after injury to the overlying epithelium is mediated by apoptosis. The authors examined the expression of the apoptosis-related modulators, Fas (receptor), Fas ligand, Bax, Bcl-2, Bcl-XL, and interleukin-1 beta converting enzyme (ICE) in corneal cells as candidate mediators of this response and tested the eff...

PURPOSE To evaluate the roles of ADP-ribosylation factor (ARF) in alkali-induced corneal neovascularization (CNV). METHODS CNV was induced by alkali injury and compared in ARF1 inhibitor- or vehicle-treated mice 3 weeks after injury. Angiogenic and apoptosis factor expression in corneas after injury was quantified with reverse-transcription PCR. Human retinal endothelial cell apoptosis induce...

PURPOSE To investigate the use of femtosecond laser cataract surgery in traumatic cataracts of different origin. METHODS The first case developed acute traumatic cataract due to penetrating injury of the cornea and the anterior lens capsule; the second developed traumatic cataract 11 years after a penetrating corneal injury; and the third developed a "white" cataract 12 months after blunt ocu...