PURPOSE To evaluate the visual outcomes, recurrence patterns, safety, and efficacy of excimer laser phototherapeutic keratectomy (PTK) in conjunction with mitomycin C (MMC) for corneal macular and granular diystrophies. METHODS The patients were divided into two groups. Group 1 included patients with macular corneal dystrophy (MCD) that caused superficial corneal plaque opacities, and Group 2...

BACKGROUND Infectious crystalline keratopathy is a rare, progressive infection characterized by the insidious progression of branches and crystalline corneal opacities with minimal or no inflammation. This case report describes the evolution of an infectious crystalline keratopathy caused by Cladosporium sp., which developed after tectonic keratoplasty in a patient with a history of ocular trau...

PURPOSE To perform a prevalence study of Punctate Keratopathy of West Indians in Colombian individuals and to propose a new name for the condition. METHODS Prospective, population-based epidemiological study. All patients evaluated between November 1 and December 31, 2012, in the Centro Oftalmológico Virgilio Galvis and Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia, w...

Dermochondral corneal dystrophy (of FranVois) has been reported rarely in the literature. It consists of a triad of findings characterised by the development of skin nodules, acquired deformities of the extremities, and a corneal dystrophy. The corneal dystrophy is central and superficial with whitish subepithelial opacities. We present two brothers who display previously unreported ocular find...

PURPOSE To describe the clinical and pathologic characteristics of a family with a congenital stromal dystrophy of the cornea and to identify the genetic basis for this disorder. METHODS All family members in three generations underwent ophthalmic examination. Stored corneal buttons were examined by transmission electron microscopy. Molecular genetic studies, including a genome-wide scan with...

Laboratory Specimens The eastern lubber grasshopper, Romalea guttata, is often used as the introduction to insect anatomy. Romalea is a large insect, reaching 50 to 75 mm in length, and is easily dissected. It is a good example of general, relatively unspecialized insect anatomy. Romalea is best studied using anesthetized living, or freshly sacrificed specimens. Preserved animals are much less ...

We describe two females with de novo X;Y translocations, who presented at birth with irregular linear areas of erythematous skin hypoplasia involving the head and neck, along with eye findings that included microphthalmia, corneal opacities, and orbital cysts. The features in these children are similar to but distinct from those seen in females with Goltz syndrome and incontinentia pigmenti. Cy...

INTRODUCTION Most chromosome 3 deletions are associated with neuro-developmental and eye abnormalities. Here, we report a rare and unusual multiple congenital abnormality, including ano-rectal malformation, in conjunction with chromosome 3q29 segment deletion, which has not previously been reported. CASE PRESENTATION A three-month-old female Jordanian baby presented with an absent anus and co...

CASE REPORT A 78-year-old man with phakic eyes underwent photodynamic therapy followed by intravitreal injection of triamcinolone. During the injection a white solution was observed in the anterior chamber. Slit lamp examination revealed white opacities in the inferior anterior chamber angle and neither inflammatory activity nor corneal changes were noticed. DISCUSSION Intravitreal triamcinol...

Clinical examination of 113 patients in South Korea with lepromatous leprosy and severe visual impairment showed that the main cause of visual loss was the combined effect of corneal and lens opacities associated with small nonreacting pupils and iris atrophy. Cataract surgery with broad iridectomy and inferior sphincterotomy offers these patients with chronic lepromatous complications the best...