Since alkaline substances can rapidly penetrate into the cornea and subsequently damage limbal stem cells, another source of stem cells may be necessary to reconstruct the ocular surface. Omentum has some such characteristics like ability to regenerate tissue as well as anti-inflammatory capacity. Presence of adult stem cells and pluripotent embryonic cell markers make it suitable in wound heal...

Most patients receive conservative treatment — lubrication of the eye to reduce symptoms related to disturbance of the tear film. About 5% of patients will need more aggressive therapy (e.g., systemic corticosteroids, orbital radiation, surgical removal of orbital walls) to prevent vision loss caused by either compression of the optic nerve by enlarging extraocular muscles or corneal ulceration...

PURPOSE To validate tissue quality parameters for donor corneas designated for emergency grafting for corneal graft survival. METHODS In a longitudinal cohort follow-up study, 131 emergency penetrating grafts were studied. Grafts were performed with a pool of organ-cultured donor corneas designated for emergency grafting and prepared for immediate use with all safety tests performed. Assignat...

Ocular setariasis is a common vision threatening ophthalmic condition in equine resulting from ectopic parasitism by Setaria digitata, equina and Thelazia lacrymalis. The disease occurs mostly summer autumn seasons it displays signs of lacrimation, photophobia, corneal opacity, conjunctivitis loss vision. Close inspection the eye reveals moving worm anterior chamber eye. B-mode ultrasonography ...

PHOTOGRAPHY WITH INFRA-RED FILM Dekking (1933, 1934) published several photographs of eyes with dense corneal opacities using infra-red film and radiation of a wave-length of about 10,000 A.u. His photographs strikingly demonstrated how infra-red radiation could penetrate a dense corneal opacity, and clearly record the appearance of the iris and pupil, which were invisible by ordinary methods o...

CASE REPORT A 75-year-old man with bilateral idiopathic lipid keratopathy underwent a penetrating keratoplasty in the left eye. One month later, there was deep corneal neovascularisation extending across the bed and the graft-host interface, with a whitish opacity surrounding the vessels. Topical bevacizumab (25mg/mL) was administered 4 times daily for 2 months with partial regression of cornea...

Several cationic-amphiphilic drugs such as chloroquine and amiodarone are known to induce phospholipidosis in the cornea by systemic administration. However, the characteristics of ophthalmological and pathological changes when phospholipidosis-inducing drugs are topically applied have not been well studied. This study was conducted to investigate the characteristics of corneal changes caused b...

BACKGROUND This study was aimed to determine the correlation between ocular complications and respiratory or cutaneous complications in a group of 40 Iranian veterans with late complications of sulphur mustard (SM) poisoning. METHODS Thorough ophthalmologic examination was performed on all severely SM-poisoned veterans in the province of Khorasan, Iran. Spirometric evaluation of pulmonary fun...

After an initial screening of ingredients and production methods, nanoemulsions for ocular administration of timolol containing the drug as maleate (TM) or as ion-pair with AOT (TM/AOT) were prepared. The physico-chemical characterization of nanoemulsions, regarding mean diameter, pH, zeta potential, osmolarity, viscosity and surface tension, underlined their feasibility to be instilled into th...

The anterior segment of the vertebrate eye is constructed by proper spatial development of cells derived from the surface ectoderm, which become corneal epithelium and lens, neuroectoderm (posterior iris and ciliary body) and cranial neural crest (corneal stroma, corneal endothelium and anterior iris). Although coordinated interactions between these different cell types are presumed to be essen...