Purpose To present anterior segment ophthalmic manifestations of Wiskott-Aldrich syndrome (WAS), a rare X-linked primary immune-deficiency. Observations A 15-year old male with WAS presented with multiple corneal ulcers of the left eye. Once resolved, this was followed by separate episodes of episcleritis in the left eye and corneal infiltrates of the right eye. Successful treatment included ...

PURPOSE To report the indications and techniques of corneal transplantation at a tertiary referral center in Tehran over a 3-year period. METHODS Records of patients who had undergone any kind of corneal transplantation at Labbafinejad Medical Center, Tehran, Iran from March 2004 to March 2007 were reviewed to determine the indications and types of corneal transplantation. RESULTS During th...

Ulcus rodens corneae (Mooren's ulcer) was studied in 30 patients with 38 corneal ulcers. Although the clinical picture resembled Mooren's description, the West African type of ulcus rodens is different in that it has a higher prevalence, a tendency towards perforation, is most frequent in the age group 20-40 years, and is often associated with ankylostomiasis. Conjunctival excision with thermoc...

MULES (1894) wrote that "where the action of micro-organisms on an abraded surface may cause or is causing destructive changes, the indication would be to remove the irritating element and allow the natural process of repair to heal the breach of surface". Thus the best results are likely to be achieved by that mode of administration which will give the maximum concentration of the drug in the ...

The purpose of this study was to assess the efficacy riboflavin/UV-A corneal phototherapy in comparison with topical antimicrobials for treatment ulcers horses. Nineteen horses a diagnosis ulceration were randomised receive either (11 horses) or antimicrobial therapy (8 horses). consisted application riboflavin-enriched ophthalmic solution onto cornea 20 min followed by UV-A irradiation at 30 m...

introduction: microbial keratitis is an infective process of the cornea with a potentially and serious visual impairments. contact lenses are a major cause of microbial keratitis in the developed countries especially among young people. therefore, the purpose of the present study was to evaluate the frequency and microbiological characteristic of clk in patients referred to the emergency depart...

The epidemiology of microbial keratitis has been investigated in several studies by analysis of organisms cultured from corneal scrapes. However, a comparison of the frequency of different organisms causing keratitis in different parts of the world is lacking. The authors present a review incorporating an analysis of data from studies worldwide. The data provide a comparison of the frequency of...

PURPOSE To compare polymerase chain reaction (PCR) to microbial culture for the detection and identification of bacterial and fungal pathogens in microbial keratitis. DESIGN Prospective cohort study. METHODS A total of 108 consecutive corneal ulcers were cultured and analyzed by PCR using pan-bacterial and pan-fungal primers. PCR products were cloned, sequenced, and compared to culture resu...