Objective: Atheromatous ascending aortic aneurysms (AAA) frequently present with aortic regurgitation (AR) from dilatation of the sinotubular junction (STJ) and extension of the pathological process into the root. Experience suggests that root dilatation begins in the noncoronary, then right coronary sinus. Rather than employ aortic root replacement or the David procedure, we have elected to re...

Primary coronary sinus tumors are extremely rare. Herein, we present a case of a pregnant woman with a primary myxoma in the coronary sinus (CS), which was diagnosed by echocardiography and computed tomography. We reviewed the literature and found two other primary CS tumors. We summarized the gender, ages, symptoms, diagnostic methods, associated anomalies, treatments, histologic findings, and...

OBJECTIVE To assess the importance of 2,3-diphosphoglycerate (2,3-DPG) and oxygen-haemoglobin binding to oxygen transport in patients with congestive heart failure. METHODS In 30 patients with severe congestive heart failure, arterial, mixed venous, and coronary sinus venous blood concentrations of 2,3-DPG were measured and systemic output and coronary sinus blood flow were measured by a ther...

Percutaneous coronary intervention (PCI) in an anomalous right coronary artery arising from the left sinus of valsalva can be technically challenging because of difficulty in selectively cannulating the vessel. We present two cases of successful stent implantation in an anomalous right coronary artery arising from the left sinus of valsalva. In both cases, we used an oversized 6 Fr Judkins left...

In 14 subjects with normal coronary arteries the mean coronary sinus blood flow was 122 25 mI/min (range, 83 to 159 ml/min). The blood flow computed per 100 g of left ventricle was 82 + 16 ml/min, which is in the range of values obtained by nitrous oxide and coincidence counting methods. In 35 patients with arteriographically confirmed coronary artery disease the mean flow was similar (128 + 20...

BACKGROUND An anomalous coronary artery from the opposite sinus of Valsalva may increase sudden death risk in children and young adults, and surgical intervention is often recommended. The impact of this lesion when recognized in the adult and its management are ill defined. METHODS AND RESULTS We reviewed 210 700 cardiac catheterizations performed over a 35-year period at a single institutio...

OBJECTIVE To investigate the release of chemoattractants after myocardial ischaemia during balloon angioplasty. DESIGN Sampling of femoral arterial and coronary sinus blood before and immediately after the first balloon inflation during angioplasty. In a study group of 16 patients the balloon was kept expanded for two minutes, whereas in a control group of eight patients the first balloon inf...

OBJECTIVE To report the uncommon association between neurofibromatosis type 1 (NF1) and unroofed coronary sinus. CASE DESCRIPTION Girl with four years and six months old who was hospitalized for heart surgery. The cardiac problem was discovered at four months of life. On physical examination, the patient presented several café-au-lait spots in the trunk and the limbs and freckling of the axil...

The effects of soman (pinacolyl methylphosphonofluoridate) on coronary blood flow, the electrocardiogram, and cardiac function were measured in alpha-chloralose-anesthetized swine. Coronary blood flow (CBF), mean arterial blood pressure (MAP), peak systolic left ventricular pressure (IVP), maximum rate of left ventricular pressure development (dP/dtmax), cardiac output, and the ECG were monitor...

INTRODUCTION Sinus of Valsalva aneurysms (SVAs) constitute about 1% of congenital cardiac anomalies and occur most commonly in patients of Asian origin. It is most commonly described in the right sinus (70%), to a lesser degree in the non-coronary, and least common in the left sinus. These aneurysms can cause aortic regurgitation, cardiac ischemia and arrhythmias. They can rupture into the righ...