نتایج جستجو برای: coronavirus

تعداد نتایج: 40719  

Journal: :Chemical communications 2007
Nan Yang Julian A Tanner Zai Wang Jian-Dong Huang Bo-Jian Zheng Nianyong Zhu Hongzhe Sun

A series of bismuth complexes were synthesized and characterized, and most of them exhibited inhibition against the SARS coronavirus helicase ATPase and duplex-unwinding activities at micromolar concentrations.

Background: The negative impacts of the Coronavirus Disease 2019 (COVID-19)outbreak on public mental health are enhancing the number of individuals requiring psychotherapy. Besides, anxiety is becoming more frequent than any other mental health issue among individuals. Similar to other anxiety types, coronavirus anxiety is associated with elevated attentional bias. The present study aimed to ex...

Background: Organizational success depends on leadership style. Leadership style probably affects coronavirus anxiety and workers’ safety behavior at work. This study aims to examine the structural association between leadership style and coronavirus anxiety with safety behavior among workers in the sanitary products industry in Qom Province. Materials & Methods: This descriptive-correlative s...

Journal: :PLoS pathogens 2016
Nerea Irigoyen Andrew E Firth Joshua D Jones Betty Y-W Chung Stuart G Siddell Ian Brierley

Members of the family Coronaviridae have the largest genomes of all RNA viruses, typically in the region of 30 kilobases. Several coronaviruses, such as Severe acute respiratory syndrome-related coronavirus (SARS-CoV) and Middle East respiratory syndrome-related coronavirus (MERS-CoV), are of medical importance, with high mortality rates and, in the case of SARS-CoV, significant pandemic potent...

Nouri Goushki, Maryam , Nozari, Majid ,

Viral infections have caused various diseases and deaths worldwide. In recent years, the emergence of the coronavirus has caused severe respiratory tract infections and led to a global concern. This study aims to investigate the effectiveness of various disinfectants that have been used to control the coronavirus. Methods: The present study is a systematic review. Data was collected through sea...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Yu Chen Hui Cai Ji'an Pan Nian Xiang Po Tien Tero Ahola Deyin Guo

The N7-methylguanosine (m7G) cap is the defining structural feature of eukaryotic mRNAs. Most eukaryotic viruses that replicate in the cytoplasm, including coronaviruses, have evolved strategies to cap their RNAs. In this report, we used a yeast genetic system to functionally screen for the cap-forming enzymes encoded by severe acute respiratory syndrome (SARS) coronavirus and identified the no...

Journal: :Clinical chemistry 2003
Jingqiang Wang Jie Wen Jingxiang Li Jianning Yin Qingyu Zhu Hao Wang Yongkui Yang E'de Qin Bo You Wei Li Xiaolei Li Shengyong Huang Ruifu Yang Xumin Zhang Ling Yang Ting Zhang Ye Yin Xiaodai Cui Xiangjun Tang Luoping Wang Bo He Lianhua Ma Tingting Lei Changqing Zeng Jianqiu Fang Jun Yu Jian Wang Huanming Yang Matthew B West Aruni Bhatnagar Youyong Lu Ningzhi Xu Siqi Liu

BACKGROUND The widespread threat of severe acute respiratory syndrome (SARS) to human life has spawned challenges to develop fast and accurate analytical methods for its early diagnosis and to create a safe antiviral vaccine for preventive use. Consequently, we thoroughly investigated the immunoreactivities with patient sera of a series of synthesized peptides from SARS-coronavirus structural p...

Journal: :Journal of clinical microbiology 1997
F Majhdi H C Minocha S Kapil

This is the first report of the isolation of a coronavirus from elk calves. Two fecal samples from elk calves with diarrhea were shown to be positive for coronavirus-like particles by electron microscopy, and the particles were propagated in the human rectal tumor-18 cell line. After 24 h, syncytia were observed, and cell culture supernatants from both samples showed hemagglutinating activity w...

2014
Anna Lundin Ronald Dijkman Tomas Bergström Nina Kann Beata Adamiak Charles Hannoun Eveline Kindler Hulda R. Jónsdóttir Doreen Muth Joeri Kint Maria Forlenza Marcel A. Müller Christian Drosten Volker Thiel Edward Trybala

Coronaviruses raise serious concerns as emerging zoonotic viruses without specific antiviral drugs available. Here we screened a collection of 16671 diverse compounds for anti-human coronavirus 229E activity and identified an inhibitor, designated K22, that specifically targets membrane-bound coronaviral RNA synthesis. K22 exerts most potent antiviral activity after virus entry during an early ...

Journal: :The Lancet. Infectious diseases 2013
Chantal B E M Reusken Bart L Haagmans Marcel A Müller Carlos Gutierrez Gert-Jan Godeke Benjamin Meyer Doreen Muth V Stalin Raj Laura Smits-De Vries Victor M Corman Jan-Felix Drexler Saskia L Smits Yasmin E El Tahir Rita De Sousa Janko van Beek Norbert Nowotny Kees van Maanen Ezequiel Hidalgo-Hermoso Berend-Jan Bosch Peter Rottier Albert Osterhaus Christian Gortázar-Schmidt Christian Drosten Marion P G Koopmans

BACKGROUND A new betacoronavirus-Middle East respiratory syndrome coronavirus (MERS-CoV)-has been identified in patients with severe acute respiratory infection. Although related viruses infect bats, molecular clock analyses have been unable to identify direct ancestors of MERS-CoV. Anecdotal exposure histories suggest that patients had been in contact with dromedary camels or goats. We investi...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید