Neuronal correlates of conditioned placing reaction of cat’s forepaw were studied. The conditioned reaction evoking by tactile stimulation of the paw’s ventral side had the same motor pattern, consisting mainly in successive flexion and extension of elbow joint, as the placing reaction evoked by paw’s dorsal side stimulation in naive animals. The activity of single neurons from the m. biceps re...

The hypothesis that amino acids act as modifiers of phospholipid biosynthesis was tested in renal cortical cells from normal rats. The rate of [14C]-choline incorporation into phospholipid in cortical slices was enhanced by the addition of lysine or arginine to the incubation medium, and reduced by phenylalanine, aspartic acid, or four other amino acids. Lysine and aspartic acid appeared to mod...

I t has been shown that thrombosis of small blood vessels is a constant pathological feature of both the generalized and local Shwartzman phenomena (1-3). Studying the dermal Shwartzman reaction, Stetson found that leukocyteplatelet thrombi occur in the small blood vessels of prepared skin shortly after the provoking intravenous injection of toxin (3). He attributed this to the development of a...

While a goal-directed movement is prepared, motor cortical neurons selectively change their activity in relation to prior information about movement direction. Only little is known, however, about the neuronal representation of partial information about this parameter. We investigated this question by training monkeys in a multidirectional centre-out pointing task. A preparatory signal provided...

The generalized Shwartzman reaction is produced in rabbits by the intravenous administration of two successive doses of endotoxin derived from Gram-negative bacteria, spaced approximately 24 hours apart; the characteristic lesion which identifies the reaction is bilateral cortical necrosis of the kidneys. This lesion results from occlusion of the glomerular capillaries by masses of homogeneous,...

An experiment was conducted on naive human subjects to measure the time benefits on finger reaction times produced by the offset of a central fixation point 200 ms before the appearance of a target stimulus in the periphery. Subjects produced a shift advancement of manual reaction times. Simultaneously, the event-related potentials were recorded. The gap paradigm induced offset visual evoked po...

The cortical sources of event-related-potentials (ERP) using realistic source models were examined in a prosaccade and antisaccade procedure. College-age participants were presented with a preparatory interval and a target that indicated the direction of the eye movement that was to be made. In some blocks a cue was given in the peripheral location where the target was to be presented and in ot...