the pharmacokinetics of levofloxacin following its single intramuscular administration (3 mg/kg) was investigated in six male buffalo calves. peak plasma level of 2.95 ± 0.13μg/ml was observed at 1 h and the drug level above mic90  in plasma was detected up to 12 h of administration. the bioavailability was 68.1 ± 5.4% and levofloxacin was bound to the plasma proteins to the extent of 19.1 ± 1....

background: osteoporosis is a preventable and treatable disorder, reported with higher prevalence patients with ulcerative colitis but their relationship is controversial. osteoporosis in these patients may be attributes to corticosteroid use, malnutrition and reduced intake of calcium and vitamin d, lower levels of sex hormones, chronic inflammation and inflammatory cytokines. the aim of study...

Five patients were identified by medical records and fluorescein angiography as having developed central serous chorioretinopathy (CSC) during corticosteroid treatment. These five and 28 previously reported corticosteroid-induced CSC occurrences were studied to clarify the differences between idiopathic CSC and corticosteroid-induced CSC. Nine previously reported occurrences of corticosteroid-i...

Corticosteroid hypersensitivity is a rare, but troublesome condition often mimicking the symptoms of the underlying disease and therefore probably underdiagnosed. Our objective is to underline the importance of increased awareness of corticosteroid hypersensitivity and of determining the tolerability to other corticosteroid preparations and thus identify a safe treatment alternative. We report ...

induction of labor is one of the most common procedures during pregnancy. various methods for cervical ripening and labor induction have been described in the obstetrics literature; but the role of corticosteroids in the process of labor is not entirely understood. this study challenged the possible role of corticosteroids in induction of labor by extra-amniotic injection through an inflated in...

conclusions using a single postsurgical dose of methylprednisolone does not significantly alter the clinical outcome after repairing tetralogy of fallot. results the only significant differences were lower incidence of bacteremia and higher incidence of hyperglycemia in the group who were used methylprednisolone. patients and methods one hundred children who underwent total repair of tetralogy ...