BACKGROUND This study tested the hypothesis that childhood-onset schizophrenia (COS) is a variant of adult-onset schizophrenia (AOS) by determining if first-degree relatives of COS probands have an increased risk for schizophrenia and schizotypal and paranoid personality disorders. METHODS Relatives of COS probands (n = 148) were compared with relatives of attention-deficit/hyperactivity diso...

Plant cell walls undergo remodeling during growth and development and are the first target of many invading pathogens. Acidic pectin (homogalacturonans) binds calcium and forms chain dimers called egg boxes and even multimers at higher calcium ion concentrations. Chitosan, the deacetylated form of chitin produced by fungi when invading plant tissues, is a cationic polymer that can interact with...

Targeting cancer cells using integrin receptor is one of the promising targeting strategies in drug delivery. In this study, we conjugated an integrin-binding ligand (GGRGDSK) peptide to chitosan oligosaccharide (COS) using sulfo-SMCC as a bifunctional linker to afford COS-SMCC-GGRGDSK. The conjugated polymer was characterized by FT-IR, (1)H NMR, (13)C NMR, and SEM. COS-SMCC-GGRGDSK did not sho...

This paper describes the temporal responses of anteroventral cochlear nucleus (AVCN) units in the chinchilla to rippled noises. Rippled noise is generated when a wideband noise is delayed and added (cos+ noise) or subtracted (cos- noise) to the undelayed noise. Renewal densities were constructed to evaluate synchronous discharges at the delay. In response to rippled noise, AVCN units which show...

Objective: This is a review of our cases and published literature on cheiro-oral syndrome (COS), to better understand its localization, etiology and outcome. Methods: In addition to our database, we reviewed the medical database (including PUBMED, BIOSIS, EMBASE, and SCOPUS) and other sources, searched by the keyword of “cheiro-oral”. The defi nition of COS was a subjective or an objective sens...

In 2011, the Swedish national tourism organisation, Visit Sweden, together with Institute, launched a campaign – Curators of Sweden (CoS) on Twitter, which ended in 2018. Each week ‘Swedish’ person was chosen as curator to tweet whatever they liked through @Sweden account. All curators were because represented ‘values, skills, and ideas’ which, according campaign, ‘all combined, makes up Sweden...

In a scenario of structural intervention situation, the On-Scene Commanders (COS) only have at their disposal data provided by one who gave alert, which are insufficient to provide secure and informed decision-making. Through quantitative, descriptive, observational, cross-sectional research, using questionnaire applied operational staff perform COS function, results survey information needs. A...

Several cell stresses induce nuclear factor-kappaB (NF-κB) activation, which include irradiation, oxidation, and UV. Interestingly, serum-starving stress-induced NF-κB activation in COS cells, but not in COS-A717 cells. COS-A717 is a mutant cell line of COS cells that is defective of the NF-κB signaling pathway. We isolated genes with compensating activity for the NF-κB pathway and one gene enc...