Two smooth muscle myosin heavy chain isoforms differ in their amino terminus by the presence [(+)insert] or absence [(-)insert] of a seven-amino acid insert. Animal studies show that the (+)insert isoform is predominantly expressed in rapidly contracting phasic muscle and the (-)insert isoform is mostly found in slowly contracting tonic muscle. The expression of the (+)insert isoform has never ...

in this paper, a single machine sequencing problem is considered in order to find the sequence of jobs minimizing the sum of the maximum earliness and tardiness with idle times (n/1/i/etmax). due to the time complexity function, this sequencing problem belongs to a class of np-hard ones. thus, a special design of a simulated annealing (sa) method is applied to solve such a hard problem. to comp...

The GammaPlan treatment planning system does not account for the leakage and scatter dose during APS repositioning. In this study, the dose delivered to the target site and its periphery from the defocus stage and intershot couch transit (couch motion from the focus to defocus position and back) associated with APS repositioning are measured for the Gamma Knife model 4C. A stereotactic head-fra...

The goal of this article is to examine the effectiveness of “for-loop” and “while-loop” statements on SCMPDS by insert sort. In this article, first of all, we present an approach to compute the execution result of “for-loop” program by “loop-invariant”, based on Hoare’s axioms for program verification. Secondly, we extend the fundamental properties of the finite sequence and complex instruction...

Ocular inserts are sterile preparations, with a thin, multilayered, drugimpregnated, solid or semisolid consistency devices placed into cul-de-sac or conjunctiva sac. They are usually made up of polymeric vehicle containing drug. Ocular drug delivery is one of the most fascinating and challenging tasks being faced by the Pharmaceutical researchers. One of the major barriers of ocular medication...

Many algorithms involve a search, and they typically require two types of test: one test checks for the element being searched for, and another test is required to check the search remains within the bounds of the data structure being searched. Both of these tests can be combined into one by using a so-called sentinel. In particular, sentinels can be used in insert sort algorithms to make them ...

This study aimed to validate a bespoke 3D-printed phantom for use in quality assurance (QA) of 6 degrees-of-freedom (6DoF) treatment couch. A novel design comprising main body with internal cube structures, was fabricated at five centres using Polylactic Acid (PLA) material, an additional produced incorporating PLA-stone hybrid material. Correctional setup shifts were determined image registrat...

PURPOSE The aim of this study was to find an optimized configuration of collimator angle, couch angle, and starting tracking phase to improve the delivery performance in terms of MLC position errors, maximal MLC leaf speed, and total beam-on time of DCAT plans with motion tracking (4D DCAT). METHOD AND MATERIALS Nontracking conformal arc plans were first created based on a single phase (maxim...

This paper studies the general meaning of the additive particle too. It is argued that besides its well-known presuppositional content, too also conveys an information regarding the similarity of its host and the antecedent of its presupposition in the discourse. We couch our proposal in an argumentative framework. This proposal is then articulated with recent accounts of the obligatoriness of ...

The purpose of this study was to compare the dosimetry of CG-Darc with three-dimensional conformal radiation therapy (3D CRT) and volumetric-modulated arc therapy (RapidArc) in the treatment of breast cancer with APBI. CG-Darc plans were generated using two tangential couch arcs combined with a simultaneous noncoplanar gantry arc. The dynamic couch arc was modeled by consecutive IMRT fields at ...