Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from updating the literature, this article focuses on clinical studies and CBD potential interactions with other drugs. Results: In general, the often described favorable safety profile of CBD in humans was confirmed and extende...

BACKGROUND Although rare, injury to the common bile duct (CBD) during laparoscopic cholecystectomy (LC) can be reduced by better intraoperative visualization of the cystic duct (CD) and CBD. The aim of this study was to establish the efficacy of early visualization of the CD and the added value of CBD identification, using near-infrared (NIR) light and the fluorescent agent indocyanine green (I...

in this paper, the crack detection and depth ratio estimation method are presented in beamlikestructures using elman networks. for this purpose, by using the frequencies of modes asinput, crack depth ratio of each element was detected as output. performance of the proposedmethod was evaluated by using three numerical scenarios of crack for fixed-simply supportedbeam consisting of a single crack...

Peroxisome proliferator-activated receptor-γ (PPARγ) has been reported to be involved in the etiology of pathological features of Alzheimer's disease (AD). Cannabidiol (CBD), a Cannabis derivative devoid of psychomimetic effects, has attracted much attention because of its promising neuroprotective properties in rat AD models, even though the mechanism responsible for such actions remains unkno...

In mice, running, clonic and tonic convulsions and lethality were assessed following transcorneal (electroshock) current or convulsant drugs, each administered alone and after cannabidiol (CBD) pretreatment. CBD prevented tonic convulsions caused by a convulsant current (CC) 99.99, and by the convulsant dose (CD) 99.99 values of gamma-aminobutyric acid (GABA) inhibitors, 3-mercaptoproprionic ac...

Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric disorders, including anxiety, psychosis, and depression. The mechanisms responsible for these effects, however, are still poorly understood. Similar to clinical antidepressant or atypical antipsychotic drugs, recent findings clearly indicate that CBD, either acutely or repeatedly administered, induces pl...

Abstract A simple method is proposed to model the open cracked beam structures. In this method, crack is modeled as a beam element. Hence cracked beam can be assumed to be a beam with stepped cross sections, and problem of determining natural frequency and mode shape of cracked beam, can be solved as determining these characteristics for a beam with different length and cross section. With this...

In order to check and eliminate the cracked eggs quickly and exactly in the process of egg products, a nondestructive testing system for eggshells based on digital signal processor (DSP) was established. The system utilized a TMS320VC33 DSP as a hardware platform, and has many functions such as controlling knock-equipment, sampling and processing the acoustics signals, judging the cracked-shell...

Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations. An international consortium of behavioral neurology, neuropsychology, and movement disorders specialists developed new criteria based on consensus and a systematic literature review. Clinical...