Transcranial direct current stimulation (tDCS) is a novel neuromodulatory tool that has seen early transition to clinical trials, although the high variability of these findings necessitates further studies in clinically relevant populations. The majority of evidence into effects of repeated tDCS is based on research in the human motor system, but it is unclear whether the long-term effects of ...

Despite the increasing use of transcranial direct current stimulation (tDCS), the physiological mechanisms underlying its effects are still largely unknown. One approach to directly investigate the effects of the neuromodulation technique on the brain is to integrate tDCS with non-invasive neuroimaging in humans. To provide new insight into the neurobiology of the method, DC stimulation (1mA, 6...

OBJECTIVES The primary objective of this study was to investigate the effects of five consecutive, daily 20-minute sessions of M1 a-tDCS on motor learning in healthy, cognitively intact, aging adults. DESIGN A total of 23 participants (51 to 69 years old) performed five consecutive, daily 20-minute sessions of a serial reaction time task (SRT task) concomitant with either anodal (n = 12) or s...

Transcranial direct current stimulation (tDCS) can modulate motor cortex excitability in the human brain. We attempted to demonstrate the cortical stimulation effect of tDCS on the primary motor cortex (M1) using functional MRI (fMRI). An fMRI study was performed for 11 right-handed healthy subjects at 1.5 T. Anodal tDCS was applied to the scalp over the central knob of the M1 in the left hemis...

Recent studies have demonstrated that transcranial direct current stimulation (tDCS) is potentially useful to improve working memory. In the present study, young and elderly subjects performed a working memory task (n-back task) during an electroencephalogram recording before and after receiving anodal, cathodal, and sham tDCS over the left dorsolateral prefrontal cortex (DLPFC). We investigate...

BACKGROUND The dorsolateral prefrontal cortex (DLPFC) has been proposed to play an important role in neural processes that underlie multitasking performance. However, this claim is underexplored in terms of direct causal evidence. OBJECTIVE The current study aimed to delineate the causal involvement of the DLPFC during multitasking by modulating neural activity with transcranial direct curren...

OBJECTIVE The authors evaluate the effectiveness of noninvasive brain stimulation, in particular, transcranial direct current stimulation (tDCS), for accelerating learning and enhancing human performance on complex tasks. BACKGROUND Developing expertise in complex tasks typically requires extended training and practice. Neuroergonomics research has suggested new methods that can accelerate le...

26 We previously demonstrated that network-level functional connectivity in the human 27 brain could be related to levels of inhibition in a major network node at baseline 28 (Stagg et al., 2014). Here, we build upon this finding to directly investigate the 29 effects of perturbing M1 GABA and resting state functional connectivity using 30 transcranial direct current stimulation (tDCS), a neuro...

conclusions our results support the use of pns in some patients with refractory chronic headaches. appropriate surgical planning and technique are important to achieve good clinical outcome and to minimize complications. background subcutaneous peripheral nerve stimulation (pns) has emerged as a useful tool in the treatment of intractable headaches. however, complications such as skin erosion, ...

Advances in neuroscience and technology brought us several methods that have potential to non-pharmacologically influence our brain. most of these methods are developed with the purpose of treating disorders, but also have favourable results on cognition and mood in the healthy, and the potential to be used for enhancement purposes. Two categories of methods are used for treatments of the brain...