The mechanism of glomerular ultrafiltration in normal kidneys or after renal injury is reviewed. The role of increased glomerular plasma flow in mediating increases of nephron filtration rate is evidenced under experimental conditions resulting in filtration pressure disequilibrium along glomerular capillaries. The increase of nephron filtration in hypertrophied kidneys appears to be due mainly...

To determine the filtration characteristics of the aqueous outflow system, microspheres (0.18 micron -1.1 micron) were perfused through enucleated human and bovine eyes. The microspheres were smaller than morphologically determined flow dimensions, and yet a significant fraction of all sizes of microspheres were captured. The bovine (calf) aqueous outflow system was found to be a far more effic...

Changes in glomerular filtration rate and effective renal plasma flow following a protein meal were measured in seven patients with essential hypertension on no treatment and after 6 weeks' treatment with nifedipine and mefruside. Glomerular filtration rate and effective renal plasma flow increased significantly following a protein meal in patients on no treatment (P less than 0.01 and P less t...

1. The mechanism of the antidiuretic effect of hydrochlorothiazide in diabetes insipidus was studied in anaesthetized Brattleboro rats with the hereditary hypothalamic form of the disease. 2. The antidiuresis caused by acute administration of hydrochlorothiazide followed an increase in sodium excretion and was associated with a significant fall in the plasma sodium concentration. There were con...

The characterization of membrane fouling provides valuable information about the performance and operational range filtration processes. parameters for purification concentration protein aggregates from cell lysates by ultrafiltration is determined evaluating resistances. We therefore investigated cross-flow ovalbumin (OVA) with a mean size 304 nm using 50 cut-off ceramic membrane. observed 90%...

Direct flow (sometimes called “dead end”) filtration is applied when all the fluid to be filtered is driven, typically in industrial applications due to a supply pressure, in a direction perpendicular to a filtering surface; few applications are done by gravity feed. Contaminants are captured within the filtration media or build up on the surface, causing the differential pressure across the fi...