Historically, antidotal potencies of cyanide antagonists were measured as increases in the experimental LD(50) for cyanide elicited by the antidotes. This required the use of high doses of cyanide following pre-treatment with the putative antidote. Since IACUC guidelines at our institutions strongly discourage LD(50) determinations: we developed a new test paradigm that allowed for maximal surv...

Differences in the action of the commonly employed respiratory inhibitors, cyanide and azide, have been described in studies on a number of tissues and microorganisms; e.g., resting and active frog muscle (1, 2)) mammalian salivary glands (3), embryonic fish hearts (4), and yeast (5). More recently differences in the action of these substances on the oxidation of various substrates by cell-free...

cyanide is one of the major environmental pollutants in industrial wastewater. entrance of it to existence environmental contains very health hazardous. the cyanide can be removed from aqueous solutions in many ways, but most of these methods are expensive. in the present study, novel magnetic nanoparticle modified with a polydentate ligand is used to remove cyanide. the procedure is efficient ...

A new family of eight dinuclear iridium(iii) complexes has been prepared, featuring 4,6-diarylpyrimidines L(y) as bis-N^C-coordinating bridging ligands. The metal ions are also coordinated by a terminal N^C^N-cyclometallating ligand L(X) based on 1,3-di(2-pyridyl)benzene, and by a monodentate chloride or cyanide. The general formula of the compounds is {IrL(X)Z}2L(y) (Z = Cl or CN). The family ...

addition of potassium cyanide to a mixture of schiff base and lithium perchlorate afforded a-aminonitriles in high yields. addition of potassium cyanide to a methanolic solution of schiff base and phosphoric acid afforded a-aminonitriles. when the reaction mixture was refluxed it gave a-amino acids in high yields.

Differences in the action of the commonly employed respiratory inhibitors, cyanide and azide, have been described in studies on a number of tissues and microorganisms; e.g., resting and active frog muscle (1, 2)) mammalian salivary glands (3), embryonic fish hearts (4), and yeast (5). More recently differences in the action of these substances on the oxidation of various substrates by cell-free...