A series of unsymmetrical silicon(IV) phthalocyanines with a permethylated β-cyclodextrin unit and a sugar or a diamino moiety as the axial substituents have been prepared. These compounds are highly photocytotoxic with IC(50) values as low as 21 nM, which is ca. sevenfold lower than those of the symmetrical bis(cyclodextrin) analogue.

To obtain direct evidence for the fullerene-exchange reactions from the γ-cyclodextrin cavities to the lipid membranes following the addition of a C70·γ-cyclodextrin complex, we monitored the dynamic behaviours of the giant unilamellar vesicles. A number of C70 aggregates generated in the lipid membranes moved about vigorously.

From the effect of β-cyclodextrin and hydroxypropyl-β-cyclodextrin on the UVvisible and fluorescence spectra of carbaryl and carbofuran, the values of association constants were determined. The ratio of the fluorescence quantum yields for the bound and free substrates indicated an enhanced fluorimetric method of detection.

Hollow mesoporous silica nanoparticles (HMSs) were modified by β-cyclodextrin via a "click" reaction, an amphiphilic copolymer with a trans-azobenzene structure was then assembled onto β-cyclodextrin to cover the surface of the HMSs. The prepared nanocomposites can release drugs in a "release-stop-release" manner by converting light irradiation.

Rhodium(0) nanoparticles stabilized by a polymer containing carboxylate and β-cyclodextrin moieties have high stability and catalytic activity for aqueous hydrogenation reactions of olefins and aromatic substrates. This catalytic system can be recycled and reused without loss of activity. These high catalytic performances can be attributed to conjugated electrostatic interactions (carboxylate g...

Gold recovery using environmentally benign chemistry is imperative from an environmental perspective. Here we report the spontaneous assembly of a one-dimensional supramolecular complex with an extended {[K(OH₂)₆][AuBr₄](α-cyclodextrin)₂}n chain superstructure formed during the rapid co-precipitation of α-cyclodextrin and KAuBr₄ in water. This phase change is selective for this gold salt, even ...

Low concentrations of cyclodextrins (< 1.0 mM) added to serum act catalytically, accelerating the exchange of cholesterol between cells and lipoproteins. J774 macrophages incubated with serum and 2-hydroxypropyl-beta-cyclodextrin (< or = 1 mM) released fivefold more labeled cholesterol than with serum alone. Increased efflux was not accompanied by a change in cell cholesterol mass; thus, cyclod...

The purpose of the present study was to prepare inclusion complex of domperidone with hydroxylpropyl-β-cyclodextrin in order improved the solubility and hence to increase dissolution of domperidone. An effect of concentration of hydroxylpropyl-β-cyclodextrin on the aqueous solubility of domperidone was determined by phase-solubility method. The aqueous solubility of domperidone increased as a f...

The synthesis of the β-cyclodextrin-5-flucytosine inclusion complex in aqueous media has been recently reported, the characterization of the complex proving the complete inclusion of the 5-flucytosine molecule into the β-cyclodextrin cavity. Still, the type of interactions that stabilize the supramolecule and the structure of the complex have been poorly described. The present paper focuses on ...

A novel β-cyclodextrin derivative 4 bearing a pyridinio group on the primary side was synthesized by the reaction of 2-aminopyridine with 6-β-cyclodextrin monoaldehyde 3, and its complexation stability constants with several aliphatic amino acids have been determined in phosphate buffer solution ( pH = 7.2, 0.1 mol L) at 25 by using spectrofluormetric titrations. The stoichiometry is 1 1 for th...