An improved synthesis of 1-O-acyl glucosyl esters that avoids the use of expensive Ag reagents as well as the hydrolysis of unstable glucosyl bromides is reported. Notably, β-configuration products were obtained exclusively in good yields.

Wound healing represents a dynamic set of coordinated physiological processes observed in response to tissue injury. Several natural products are known to accelerate the process of wound healing. Tetrahydrocurcumin (THC), an in vivo biotransformed product/metabolite of curcumin, is known to exhibit a wide spectrum of biological activities similar to those of native curcuminoids. The poor bioava...

Phosphatidylmonoglucosyl diacylglycerol of Pseudomonas diminutu is biosynthesized from [14C]glycerolor 32Plabeled phosphatidylglycerol and [Wlglycerolor [‘4C]glucase-labeled 3-O-(ru-o-glucopyranosyl)-1,2-diacyl-sn-glycerol (glucosyl diacylglycerol) by a transphosphatidylation reaction. Diphosphatidylglycerol and kojibiosyl diacylglycerol which are substrates in a transphosphatidylation catalyze...

Solubilization and partial purification of the microsomal UDP-glucose sterol glucosyl transferase activity from maize coleoptiles by chromatography on DEAE-cellulose resulted in a highly delipidated (>95%) and inactive enzymic preparation. Addition of sterols revealed part of the activity and subsequent addition of phospholipids further increased the activity. Negatively charged phospholipids w...

The monoterpene ketone l-menthone is specifically converted to l-menthol and l-menthyl acetate and to d-neomenthol and d-neomenthyl-beta-d-glucoside in mature peppermint (Mentha piperita L. cv. Black Mitcham) leaves. The selectivity of product formation results from compartmentation of the menthol dehydrogenase with the acetyl transferase and that of the neomenthol dehydrogenase with the glucos...

The abilities of a family of chemically synthesized oligo-beta-glucosides, ranging in size from hexamer to decamer, to induce phytoalexin accumulation in soybean cotyledons were investigated to determine which structural elements of the oligoglucosides are important for their biological activity. The results of the biological assays established that the following structural motif is necessary f...

An improved synthesis of glucosyl esters was reported here, avoiding the use of expensive Ag reagent as well as the hydrolysis of instable glucosyl bromide. Notably, -configuration product was exclusively obtained in good yield.

Mycobacteria synthesize intracellular methylglucose lipopolysaccharides (MGLP) proposed to regulate fatty acid synthesis. Although their structures have been elucidated, the identity of most biosynthetic genes remains unknown. The first step in MGLP biosynthesis is catalyzed by a glucosyl-3-phosphoglycerate synthase (GpgS, Rv1208 in Mycobacterium tuberculosis H37Rv). However, a typical glucosyl...

background: the complexity of the fermentation processes is mainly due to the complex nature of the biological systems which follow the life in a non-linear manner. joined performance of artificial neural network (ann) and genetic algorithm (ga) in finding optimal solutions in experimentation has found to be superior compared to the statistical methods. range of applications of β-cyclodextrin (...