Apocrine neoplasms are rare in goats. This report describes an apocrine adenocarcinoma a 5-year-old female Boer goat with ulcerated, exophytic, multilobulated mass on the left dorsolateral cervical area. Histologically, dermis was effaced and expanded by poorly demarcated epithelial neoplasm desmoplasia. Neoplastic cells were arranged acini papillary projections into lumen had cuboidal or colum...

Leukemic myeloblasts containing abnormal granules were studied with ultrastructural, cytochemical, and thymidine labeling techniques to evaluate defects in granulogenesis and proliferation. Giant granules (1 to 3 micron in diameter) and Auer rods were observed in leukemic cells from two patients, and only rarely were both abnormal granule types observed in the same cell. The lysosomal origin of...

The regulation of translation and mRNA degradation in eukaryotic cells involves the formation of cytoplasmic mRNP granules referred to as P-bodies and stress granules. The yeast Pbp1 protein and its mammalian ortholog, Ataxin-2, localize to stress granules and promote their formation. In Saccharomyces cerevisiae, Pbp1 also interacts with the Pab1, Lsm12, Pbp4, and Dhh1 proteins. In this work, w...

Leukemic myeloblasts containing abnormal granules were studied with ultrastructural, cytochemical, and thymidine label ing techniques to evaluate defects in granulogenesis and pro liferation. Giant granules (1 to 3 /im in diameter) and Auer rods were observed in leukemic cells from two patients, and only rarely were both abnormal granule types observed in the same cell. The lysosomal origin of ...