Food fortification is an effective intervention strategy for combating micronutrient deficiencies. Vitamin A can be fortified in a wide range of food vehicles. In this research work, vitamin the form palmitate (VAP) have been microencapsulated by emulsion technology intended purposes. D-optimal mixture design approach was applied optimizing experimental process parameters. Detailed physico-chem...

The smart chemical laboratory has recently emerged as a promising trend for future research, where experiment optimization is of vital importance. traditional Bayesian (BO) algorithm focuses on exploring the dependent variable space while overlooking independent space. Consequently, BO suffers from becoming stuck at local optima, which severely deteriorates performance, especially with bad-qual...

In this paper, we propose two simple yet efficient computational algorithms to obtain approximate optimal designs for multi-dimensional linear regression on a large variety of design spaces. We focus the commonly used criteria, D- and A-optimal criteria. For D-optimality, provide an alternative proof monotonic convergence D-optimal criterion algorithm design. further show that proposed converge...