The effect of the protein kinase C (PKC) inhibitor staurosporine (ST) on the chemosensitivity of normal (colony-forming unit granulocyte-macrophage [CFU-GM]) and leukemic (acute myeloid leukemia-CFU [AML-CFU]) myeloid progenitors to daunorubicin (DNR) was evaluated. Primary colony inhibition assays allowed us to characterize two distinct groups of AML, a DNR-resistant group (patients no. 1 thro...

Polylactide-glycolide (PLGA) nanoparticles have been developed as pulmonary drug delivery carriers. To investigate their behavior, small- (d50 = 74 nm) and large-sized (d50 = 250 nm) FITC-conjugated PLGA nanoparticles were intratracheally administered to rats and were traced for 5, 30 and 60 minutes and 24 hours after administration (HAT). Immunohistochemically, a, FITC-positive reaction was ob...

abstract spacing between check dams depends on the stream bed slope, effective height of check dams and slope of deposited sediments behind the check dams. the slope of deposited sediments is more important than the other two factors because of complications in the way of its occurrence and its measurement after several years of dam construction. this research presents the effective factors aff...

The electrostatic atomization effect of liquid in high voltage field was studied under capillary-flat electrodes. effects charging voltage, flow rate, and the distance between a capillary flat electrode on droplet size distribution were analyzed by DP-02 laser particle analyzer. single-factor method used to analyze effects. experimental results show that plate greatly influence droplet's effect...

The aim of the present study was to evaluate the difference in treatment plan quality, monitor units (MUs) per fraction and dosimetric parameters between IMRT (intensity-modulated radiotherapy) and RapidArc with single arc (RA1) and dual arc (RA2) for malignant glioma involving the parietal lobe. Treatment plans for IMRT and RA1 and RA2 were prepared for 10 patients with malignant gliomas invol...

PURPOSE To examine the relationship between uncorrected residual wavefront error and visual performance (VP) in rigid gas permeable (RGP) contact lens-wearing keratoconic eyes. METHODS Seven eyes from six subjects (six moderate, one severe) were studied (mean +/- SD age: 42.71 +/- 11.38 years). Significant corneal scarring was an exclusion criterion. Measurements were taken with RGP lenses in...

This essay surveys the literature on directed search and competitive equilibrium, covering theory a variety of applications. These models share features with traditional theory, but also differ in important ways. They general equilibrium explicit frictions. Equilibria are often efficient, mainly because markets price goods plus time required to get them. The approach is tractable arguably reali...