vitamin b6 is a cofactor of various enzymes influencing numerous neurotransmitters in the brain such as norepinephrin, and serotonin . since these neurotransmitters influence mood , the aim the present work to evaluate the effect of vitamin b6 on depression and obsessive compulsive behavior when coadministred with clomipramine, fluoxetine, or venlafaxine. male mice weighing 25-30 g were used. t...

objective: the methylenetetrahydrofolate reductase (mthfr) gene polymorphism c677t is suspected to be a risk factor for psychiatric disorders, but it remains inconclusive whether the mthfr polymorphism c677t is imputed to vulnerability to schizophrenia and bipolar disorder. method: we prompted impetus to appraise this polymorphism in an iranian population. therefore, 90 patients with bipolar di...

both at11th edition of the international classification of diseases (icd-11) and in fifth edition of the diagnostic and statistical manual of mental disorders (fifth edition-dsm-5), have pointed out that attitudes and quality of sleep can be seriously impaired by post-traumatic stress disorder (ptsd). the present study was conducted to compare hostility and sleep disorders among nursing student...

cognitive appraisals of the trauma play a key role in children’s adjustment following a traumatic event, but how these appraisals develop is not well understood. cognitive models of posttraumatic stress disorder (ptsd) suggest that social support is a key influence on the development of appraisals, and we aimed to explore this relationship further. as predicted by cognitive models of ptsd, we h...

post traumatic stress disorder (ptsd) is a disorder of emotional and mental stress occurring as an outcome of injury or severe emotional shock. yoga may be useful in decrease of ptsd symptomology. new studies demonstrate that people suffering from ptsd can find actual relief with yoga. yoga decreases stress-induced allosteric load in three reactive systems of stress: the autonomic nervous syste...

introduction: previous studies have emphasized the importance of early detection of children with developmental coordination disorder (dcd) to prevent the development of secondary academic, emotional and social manifestations of the disorder. a better understanding of these issues is the need for a valid measurement tool. parent report has the potential for providing historical knowledge of the...

background : the present study aimed to determine the relationship between mental disorders and burnout among employees of shiraz university of medical science, iran. methods: in this cross-sectional study, 300 employees were selected as the study sample using random sampling method. symptoms of mental disorder, predictor variables, and burnout were the criterion variables of this study. data w...

results there was no statistically significant difference between the mmse scores of the two groups before surgery (p = 0.6), but the mmse test conducted at the pacu revealed significantly better cognitive outcomes in the d group than in the r group in patients younger and older than 65 years (p = 0.03 and p = 0.0001, respectively). conclusions this study revealed that dexmedetomidine may be a ...

conclusions the findings of this study are in accordance with findings from previous studies, and generally show a meaningful association between schema, emotion regulation, dissociative experiences, and suicide ideation with borderline personality features. results the results showed a significant positive correlation between schema, emotion regulation, dissociative experiences and suicide ide...

conclusion premenstrual disorders are common in adolescent girls. preventive and treatment strategies are highly recommended. background premenstrual disorders usually refer to premenstrual syndrome (pms) and premenstrual dysphoric disorder (pmdd). this study was designed to find out the frequency of premenstrual disorders and evaluate the associated factors in a sample of iranian adolescents. ...