نتایج جستجو برای: degradation and dissolution rate

تعداد نتایج: 16906759  

Journal: :international journal of environmental research 0
e. safari department of civil engineering, queen’s university, ellis hall, 58 university avenue, kingston, ontario, k7l 3n6, canada m. jalili ghazizade graduate faculty of environment, university of tehran, p.o.b.14155-6135, tehran, iran a. shokouh department of civil and environmental engineering, amirkabir technical university, tehran, iran gh.r. nabi bidhendi graduate faculty of environment, university of tehran, p.o.b.14155-6135, tehran, iran

high strength fresh leachates generated at a new disposal trench, compost plant and partially stabilized leachate of an older trench were characterized in terms of anaerobic degradation at laboratory batch scale at 35oc. fresh leachate had extremely high cod of 66,710 – 89,501 mg/l along with low ph of 4.1-5.9 in contrast to older and therefore partially stabilized leachate with a cod of about ...

2007
MICHAEL U. UHUMWANGHO ROLAND S. OKOR

The dissolution characteristics of melt granulations of paracetamol in capsule and tablet dosage form were compared to determine whether the dissolution characteristics of the granules can be actualized by formulating them as rapidly disintegrating tablets. The term melt granulation refers here to the wax-matrix granules that were formed by triturating the drug powder (paracetamol) with a melte...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Adam V Subhas Jess F Adkins Nick E Rollins John Naviaux Jonathan Erez William M Berelson

Near-equilibrium calcite dissolution in seawater contributes significantly to the regulation of atmospheric [Formula: see text] on 1,000-y timescales. Despite many studies on far-from-equilibrium dissolution, little is known about the detailed mechanisms responsible for calcite dissolution in seawater. In this paper, we dissolve 13C-labeled calcites in natural seawater. We show that the time-ev...

Gitika Arorac Harish Durejab Manju Nagpal, Pankaj Rakha Surender Goyal Veerendra Rajpurohit

      In order to enhance in vitro dissolution and content uniformity of poorly soluble drug glimepiride by preparing solid dispersions using modified solvent fusion method, solid dispersions of drug were prepared by modified fusion solvent method using PEG 6000 and PVP K25 (as carrier). Eight batches (F1-F8) were prepared by Factorial design (23) by taking three ...

2013
Malihe Shahbaziniaz Seyed Mohsen Foroutan Noushin Bolourchian

Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...

2012
Hardik Patel M. M. Patel

Controlled porosity osmotic tablet of carvedilol phosphate prepared and evaluated in this study. Carvedilol phosphate is very low soluble drug. So it is difficult to formulate osmotic tablet of carvedilol phosphate which gives drug release up to 24 hr at zero order. To get desired dissolution profile various formulation parameters like osmogen concentration, level of weight gain and level of po...

2013
Emilia Szymanska Katarzyna Winnicka

Purpose: To evaluate the usefulness of the flow-through cell apparatus for testing commercial vaginal tablets containing poorly water-soluble clotrimazole. Methods: The effect of experimental conditions (type of dissolution medium, flow rate and positioning of the tablet) on the dissolution profile of clotrimazole were examined and optimal parameters for conducting the experiments were determin...

Journal: :Acta pharmaceutica 2011
Vikas A Saharan Pratim K Choudhury

The poorly water soluble antidiabetic drug gliclazide was selected to study the effect of excipients on dissolution rate enhancement. Ordered mixtures of micronized gliclazide with lactose, mannitol, sorbitol, maltitol and sodium chloride were prepared by manual shaking of glass vials containing the drug and excipient(s). Different water soluble excipients, addition of surfactant and superdisin...

Journal: :iranian journal of pharmaceutical sciences 0
supriya patil research group department of pharmaceutics and quality assurance, shree santkrupa college of pharmacy, ghogaon, karad 415111 ms, (india) vinit patil department of pharmaceutical technology, bharati vidyapeeth college of pharmacy kolhapur, ms, india amol shete research group department of pharmaceutics and quality assurance, shree santkrupa college of pharmacy, ghogaon, karad 415111 ms, (india), rajendra doijad research group department of pharmaceutics and quality assurance, shree santkrupa college of pharmacy, ghogaon, karad 415111 ms, (india),

the objectives of present investigations were to optimize concentration of oil, surfactant and cosurfactant by pseudoternary phase diagrams and to develop a stable formulation of self emulsifying drug delivery system (sedds) in order to enhance the dissolution rate of poorly soluble irbesartan (ibs) by sedds. pseudoternary phase diagrams were constructed to identify the self emulsifying region....

2012
Edgar Alejandro Pachon-Rodriguez Jean Colombani

In the context of the study of the wet creep of plasterboards, we have performed digital holographic interferometry measurements of the dissolution of gypsum of various quarries in water and in aqueous solutions of salts inhibiting dissolution, and of the dissolution of anhydrite in water. This technique is carried out in still water and permits to observe directly the reacting solid-liquid int...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید