OBJECTIVE Clinical, familial, and, more recently, genetic linkage studies suggest that overlapping genetic susceptibility might contribute to both schizophrenia and bipolar disorder. To identify a potential psychotic dimension common to families of both bipolar and schizophrenia probands, the authors tested if delusional proneness was observed among first-degree relatives of bipolar and schizop...

BACKGROUND & OBJECTIVES A genetic link between diabetes and depression has been proposed, but hardly explored. Data on family studies exploring relation between depression and diabetes are scanty. This study attempted to assess the prevalence of major affective disorders in first-degree relatives of patients with type 2 diabetes mellitus (T 2 DM). METHODS Fifty probands with T 2 DM, in whom o...

Background: Diabetes may influence the bone in multiple pathways, some with contradictory effects. These mechanisms include changes in insulin and hypercalciuria, phophatemia, hypomagnesaemia associated with glycosuria. We tried to find out level of minerals in first degree relatives of patients with diabetes mellitus as there is relationship between bone minerals and glycemic controls. Methods...

objective: schizophrenia and other psychoses have devastating personal and social impacts and many efforts have been devoted to study ‎prodromal syndromes for psychosis in order to achieve earlier detection and interventions. however, only few studies have been ‎performed in developing countries on this subject, and there is a dearth of evidence in the iranian population. in this study, we ‎foc...