Dear Editor, I read with interest the article by Yazdani, M, et al, on the administration of magnesium sulfate to women with premature labor and its effect on the bleeding time, published in the Iranian Journal of Medical Sciences.1I found it interesting but I would like to make some points regarding to this study:There are several methods for the measurement of bleeding time (BT). Those includ...

In this paper, we propose a practical method for solving the delivery scheduling problem and discuss its implementation. The method is based on the cooperative problem solving with multiple agents. In the truck delivery scheduling method, the covered region is partitioned into multiple sub-regions and each sub-region is assigned a sub-problem solving agent. For integrating those subproblem solv...

Compared to vaginal deliveries, surgical (cesarean) deliveries are associated with more complications, longer recovery, lower satisfaction, and greater risk of postpartum mood disturbances. Despite a steep rise in rates of surgical delivery, there have been few theoretically founded investigations of the mechanisms by which delivery method has an effect on psychosocial outcome. We tested a mode...

BACKGROUND Studies on the primiparous mothers' decision on delivery method are limited. AIM The aim of his study was to determine the factors that influence the choice of delivery method by Iranian primiparous women. METHODS This cross-sectional study was conducted in April through September 2014. Participants were 460 primiparous women in 8 hospitals of 4 cities in Iran. Finally, 230 cesar...

background: progress in the field of biology and biochemistry has led to the discovery of numerous bioactive peptides and proteins in the last few decades. delivery of therapeutic proteins/peptides has received a considerable amount of attention in recent years. methods: in this study, a two-step desolvation method was used to produce biodegradable hydrophilic gelatin nanoparticles (gnp) as a d...

objective(s): lipid-based nanoparticles (nlp) are pegylated carriers composed of lipids and encapsulated nucleic acids with a diameter less than 100 nm. the presence of peg in the nlp formulation improves the particle pharmacokinetic behavior. the purpose of this study was to prepare and characterize nlps containing mdr1 sirna and evaluate their cytotoxicity and cellular uptake. mdr1 sirna coul...

microspheres formulated from poly (d,l-lactic-co-glycolide) (plga), a biodegradable polymer, have been extensively evaluated as a drug delivery system. in this study, the preparation, characterization and drug release properties of the plga microspheres were evaluated. simvastatin (sim)-loaded plga microspheres were prepared by oil-in-water emulsion/solvent evaporation method. the microspheres ...

BACKGROUND Determining the exact timing of reward delivery is critical in neurophysiological experiments. Despite the importance of this parameter, techniques for precisely measuring the exact delivery time of a liquid reward have been underdeveloped. Although there is always some latency between the computer command and reward delivery, the former has been used routinely to mark reward onset t...

Rapid mechanical deformation of cells has emerged as a promising, vector-free method for intracellular delivery of macromolecules and nanomaterials. This technology has shown potential in addressing previously challenging applications; including, delivery to primary immune cells, cell reprogramming, carbon nanotube, and quantum dot delivery. This vector-free microfluidic platform relies on mech...