The delta 2 glutamate receptors are prominently expressed in Purkinje cells and are thought to play a key role in the induction of cerebellar long-term depression. The synaptic and subsynaptic localization of delta receptors in rat cerebellar cortex was investigated with sensitive and high-resolution immunogold procedures. After postembedding incubation with an antibody raised to a C-terminal p...

OBJECTIVE The effects on cortical rhythms of a single-dose (30 microg/kg) administration of the GABAA agonist lorazepam were examined in a randomized, double-blind, cross-over, placebo-controlled study with 8 healthy volunteers using simultaneous electroencephalography (EEG) and magnetoencephalography (MEG). METHODS The oscillations were assessed by means of adaptive classification of short-t...

The PA200 proteasome activator is a broadly expressed nuclear protein. Although how PA200 normally functions is not fully understood, it has been suggested to be involved in the repair of DNA double-strand breaks (DSBs). The PA200 gene (Psme4) is composed of 45 coding exons spanning 108 kb on mouse chromosome 11. We generated a PA200 null allele (PA200(Delta)) through Cre-loxP-mediated interchr...

We employed gene targeting to study H2AX, a histone variant phosphorylated in chromatin surrounding DNA double-strand breaks. Mice deficient for both H2AX and p53 (H(delta/delta)P(-/-)) rapidly developed immature T and B lymphomas and solid tumors. Moreover, H2AX haploinsufficiency caused genomic instability in normal cells and, on a p53-deficient background, early onset of various tumors inclu...

We report that M. tuberculosis organisms, but neither PHA nor allogeneic stimulator cells, preferentially activate gamma/delta+ cells within E rosette-purified peripheral blood T cells. gamma/delta+ T cells from purified protein derivative (PPD)-nonimmune healthy donors were enriched by depletion of CD4+ and CD8+ cells; double-negative (DN) cells contained 65-92% gamma/delta+ T cells. Limiting ...

The aim of this paper is to show that under some mild conditions a functional equation of multiplicative $(alpha,beta)$-derivation is superstable on standard operator algebras. Furthermore, we prove that this generalized derivation can be a continuous and an inner $(alpha,beta)$-derivation.

Draft 3 of 3D-HEVC Test Model Description Ed. Notes (WD3) (changes compare to JCT3V-B1005):  ----------Release d1 ---------- (3DC-GT2) Editorial improvements, small corrections.  ----------Release d0 ---------- Split of Test Model text and specification text  (3DE-05) Alignment with MV-HEVC draft 3.  (3DE-01) Reordered sub-clauses related to disparity estimation and additional motion cand...

Double-strand DNA breaks are the most lethal type of DNA damage induced by ionizing radiations. Previously, we reported that double-strand DNA breaks can be enzymatically produced from two DNA damages located on opposite DNA strands 18 or 30 base pairs apart in a cell-free double-strand DNA break formation assay (Vispé, S., and Satoh, M. S. (2000) J. Biol. Chem. 275, 27386-27392). In the assay ...

Nonperturbative terms in the free energy of Chern-Simons gauge theory play a key role in its duality to the closed topological string. We show that these terms are reproduced by performing a double scaling limit near the point where the perturbation expansion diverges. This leads to a derivation of closed string theory from this large-N gauge theory along the lines of noncritical string theorie...

Abstract. The present study addresses the potential of airborne NASA – ISRO Synthetic Aperture Radar (NISAR) compact polarimetric (CP) data to discriminate land cover classes emphasizing urban area for parts Ahmedabad city, India. This has been carried out by generating m-Delta, m-Chi and m-Alpha decompositions using Compact Polarimetric L band NISAR data. In Hybrid data, both m-delta m-chi hav...