BackgroundAnti-CD20 antibody therapy may be associated with an increased risk of infections. We therefore investigated factors for infection in patients demyelinating diseases treated anti-CD20 therapy.MethodsIn this retrospective uncontrolled study, ever antibodies at academic clinic were identified through the Danish Multiple Sclerosis Registry (DMSR). Data collected from medical charts and D...

Trigeminal sensory neuropathy may result from a wide variety of factors , including tumors of the trigeminal ganglion or spinal trigeminal tract, demyelinating diseases, and connective tissue disorders. Despite a long list of possibilities, the cause often is difficult to establish , and thus many cases are described as idiopathic. We report an unusual case of trigeminal sensory neuropathy caus...

OBJECTIVE: To correlate Guillain-Barré as a consequence of the Post-COVID-19 syndrome, evaluating pathophysiological, immunogenic and epidemiological mechanisms. METHODOLOGY: A systematic review was carried out, with secondary data, using articles published in following databases: Latin American Caribbean Literature on Science Health (LILACS), Scientific Electronic Library (ScIELO) Pubmed; desc...

Leukodystrophy is a group of demyelinating neurodegenerative diseases of brain with varied presentation and multiple etiologies. Prognosis is predominantly dismal. Misdiagnosis and wrong treatment are common in this group of rare neurological disorders, especially when it presents with psychiatric symptoms. In this case, importance of neurological and radiological evaluation and need for high d...

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and astrocytes constitute macroglia. This review deals with the recent progress related to the origin and differentiation of the oligodendrocytes, their relationships to other neural cells, and functional neuroglial interactions under physiological conditions and in demyelinating diseases. One of the problems in stu...

The purpose of this review is to illustrate the wide spectrum of lesions in the corpus callosum, both congenital and acquired: developmental abnormalities, phakomatoses, neurometabolic disorders, demyelinating diseases, infection and inflammation, vascular lesions, neoplasms, traumatic and iatrogenic injury, and others. Cases include fetuses, children, and adults with rich iconography from the ...

Treatments for multiple sclerosis therapy are rapidly evolving. It is believed that new drugs will be approved in the near future, thereby changing current indications for treatment. In this context, the Spanish Society of Neurology's study group on demyelinating diseases, which evaluates medication use in MS, has decided to draw up a consensus statement on the current indications and guideline...