Sanjad-Sakati syndrome (SSS) is a rare genetic disorder with autosomal recessive pattern of inheritance characterized by hypoparathyroidism, sever growth failure, mental retardation, susceptibility to chest infection, and dentofacial anomalies. A child with SSS was referred to the dental departmentseeking dental help for sever dental caries which was attributed to his dietary habits and quality...

Dental plaques are the biofilms or the microbial population associated with the oral cavity and is responsible for several clinical conditions that affect the host system. Despite the fact that, the oral micro flora offer certain benefit to the host by offering protection to the epithelial cell from damage and enhances the digestion of some substrates, their harmful consequences cannot be denie...

Genomics research is rapidly increasing our understanding of the genetic basis of normal and abnormal growth, development, and disease. Genetic information and technologies are also being applied to develop new diagnostic and treatment strategies. Many diseases with dental, oral, and craniofacial manifestations have a genetic basis. Effective clinical application of genomics to oral medicine wi...

The current explosive growth in developmental biology, fuelled by the almost completed sequencing of the human genome, is bound to have a profound impact upon the practice of medicine and dentistry in the twenty-first century. No other discipline more accurately reflects this impact than embryology, which combines the basic and clinical sciences of genetics, ontogeny, phylogeny, teratology, and...

Previous studies have demonstrated that the presence of lactic acid bacteria (LAB), especially those classified into the genus Lactobacillus, is associated with the progression of dental caries in preschool children. Nevertheless, the kinds of species of LAB and the characteristics that are important for dental caries have been unclear. The aims of this study were: (1) to investigate the distri...

There have been no previous studies on dental maturation of prematurely born, very low birthweight (< 1500 g, VLBW) Caucasian children. This study investigated dental development and prevalence of enamel defects in a group of 55 VLBW children (mean age at dental examination 7.7 +/- 2.2 years, mean birthweight 1203 +/- 240 g, and mean gestational age 29.8 +/- 2.4 weeks) compared to 55 normal bir...

Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate angiogenic growth factors. In this study, human dental pulp stem cells (DPSCs) and stem cells from the apical papilla (SCAPs) were applied in an in vivo model of dental pulp regeneration in order to compare their regenerative potential and con...

AIM Many studies have been made to evaluate the growth, development and maturation of cervical vertebrae. These studies make clear how those vertebrae have growth patterns and centre of ossification similar to those in carpal bones, therefore cervical vertebrae can be used to determine bone age. The aim of the present study is the observation of cervical vertebrae in cephalometric radiographs t...

BACKGROUND Dental pulp stem cells (DPSCs) play an important role in tissue regeneration. This study compares the growth kinetics and characterization of third molar and first premolar human DPSCs. MATERIAL AND METHODS Dental pulp tissues were isolated from human first premolar and third molar teeth and were digested by treating them with collagenase type I. Single-cell suspensions from each d...