Aim: Dental pulp has various characteristics in the pulp chamber, but only a few biological evaluations about the effect of age on dental pulp tissue have been reported. The purpose of this study was to compare dental pulp from young and from adult rats to characterize the homeostatic mechanism. Methodology: Dental pulp cells (DPCs) were obtained from the first molar of rats, weighing 150 g eac...

objective: bioactive glass is often used as a filler material for repair of dental bone defects. in different studies osteogenic potential of this material was proved, but its dentinogenesis property is in doubt. the purpose of this study was to evaluate the histological pulp responses of calcium hydroxide and bioactive glass placed directly on exposed pulp tissues. materials and methods: twent...

The metabolic activity in dental plaque, the biofilm at the tooth surface, is the driving force behind any loss of mineral from the tooth or cavity surface. The symptoms of the process (the lesion) reflect this activity and can be modified by altering the biofilm, most conveniently by disturbing it by brushing with a fluoride-containing toothpaste. The role of operative dentistry in caries mana...

Introduction: Complicated crown fractures involve enamel, dentin, and pulp and occur in 0.9 to l3% of all dental injuries. If left untreated, will always result in pulp necrosis but, if it handled correctly, prognosis of the pulp following a traumatic crown fracture can be favorable. Case Report: The present case report describes an apexogenesis report of a 9-year old boy referred to department...

With the growing number of air passengers, flight at­ tendants, leisure pilots, as well as military and airline pilots, dentists may encounter physiological and patho­ logical phenomena precipitated by high altitude. With the introduction of the self-contained breathing appa­ ratus (SCUBA), many of these manifestations caused by changes in atmospheric pressure were reported in association with ...

The aim of this study was to examine the effect of Biodentine® and two new nanostructured materials based on active silicate cements on exposed tooth pulp of Vietnamese pigs. The study comprised 40 teeth in two Vietnamese pigs (24 months old). After class V cavity preparation, the pulp on each tooth was exposed using a small round bur. The following materials were applied on pulp exposures: Bio...

Lysophosphatidic acid (LPA) is a locally produced bioactive phospholipid which is involved in tissue repair. The objective of this study was to determine whether dental pulp tissue also responds to the phospholipid. Effects of LPA on proliferation, differentiation, and mitogen-activated protein kinase (MAPK) signaling of dental pulp fibroblasts (DPF) were examined in vitro. We report that DPF e...

The purpose of this study was to investigate dentin-bridge formation in teeth following the transplantation of dental pulp-derived cells seeded on hydroxyapatite/tricalcium phosphate (HA/TCP) scaffolds. The dental pulp tissues were removed from the extracted first molar teeth of miniature pigs and single cell populations were subcultured. Second-passage cells that had alkaline phosphatase activ...