We have synthesized the first {Mn( iii )OH} complex in an all O-donor environment K 2 [Mn(OH)(pin F ) ], 3, formed by deprotonation of corresponding )OH } complex, K[Mn(OH )(pin 1. Complex 3 oxidizes substrates with weak N–H and O–H bonds.
Journal:
:Journal of the American Chemical Society2007
Ian L AlbertsYanli WangTamar Schlick
DNA polymerases are crucial constituents of the complex cellular machinery for replicating and repairing DNA. Discerning mechanistic pathways of DNA polymerase on the atomic level is important for revealing the origin of fidelity discrimination. Mammalian DNA polymerase beta (pol beta), a small (39 kDa) member of the X-family, represents an excellent model system to investigate polymerase mecha...
