INTRODUCTION It is impractical to perform polysomnography (PSG) in all surgical patients suspected of having sleep disordered breathing (SDB). We investigated the role of nocturnal oximetry in diagnosing SDB in surgical patients. METHOD All patients 18 years and older who visited the preoperative clinics for scheduled inpatient surgery were approached for study participation. Patients expecte...

The relationship between sleep disorders and bronchiectasis has not been well described. We hypothesize that, due to the irreversible dilatation of the bronchi, the presence of secretions, and airflow obstruction, patients with non-cystic fibrosis bronchiectasis may be predisposed to hypoxemia during sleep, or to symptoms that may lead to arousal. A cross-sectional observational study was perfo...

Editor—The Onyx Liquid Embolic System (Onyx; Micro Therapeutics, Inc., Irvine, CA, USA) is a new non-adhesive liquid embolic agent and is currently being used at our institution in the embolization of cerebral vascular lesions. The disadvantage of Onyx is that it is dissolved in dimethyl sulphoxide (DMSO). Systemic toxicity, such as pulmonary oedema, bronchospasm, bradyarrhythmia, and even card...

Photosynthesizing flax, soybean, and safflower plants were exposed to 14CO2 at seed-setting stage for a 1 hr period. Seed was sampled periodically thereafter and the lipids were extracted. A triglyceride-rich fraction was methanolyzed ; the resultant methyl esters were analyzed by gas-liquid chromatography and assayed for radioactivity. Of the ClS unsaturated acids, oleic was the first to acqui...

Obesity hypoventilation syndrome (OHS) is defined as obesity (body mass index, >30 kg/m2) with daytime hypoventilation (PCO2, >45 mmHg) that is not secondary to cardiopulmonary or neurologic disease. Around 80–90% of the patients with OHS have obstructive sleep apnea and severe arterial oxygen desaturation. Obstructive sleep apnea has been found to be associated with a variety of eye diseases, ...

A 3-year-old boy presented with brainstem astrocytoma and central alveolar hypoventilation syndrome. Contrast MRI of the brain showed that the tumor involved the cerebellum, with compression of brainstem, and resolved after surgical resection. Polysomnography performed before and after total tumor resection showed significant improvement in nocturnal respiratory rate, respiratory disturbance in...

Desaturation of [1-r4C]stearic acid, [lJ4C]palmitic acid, and [l-14C]stearoyl-CoA was measured in homogenates of lo-day-old rat brain. Desaturation was maximal with stearoyl-CoA at pH 6.0 to 6.6. With free fatty acids, monoene formation was maximal at pH 7.2 to 7.6; stearic acid was more actively desaturated than palmitic acid. Activity with stearic acid or stearoyl-CoA was linear with protein ...

Rapid arterial O(2) desaturation during apnea in the preterm infant has obvious clinical implications but to date no adequate explanation for why it exists. Understanding the factors influencing the rate of arterial O(2) desaturation during apnea (Sa(O)₂) is complicated by the non-linear O(2) dissociation curve, falling pulmonary O(2) uptake, and by the fact that O(2) desaturation is biphasic, ...

BACKGROUND Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular diseases. Although CPAP is the first treatment choice for moderate-to-severe OSA, acceptance of and adherence to CPAP remain problematic. High CPAP adherence is generally defined as ≥4 h of use/night for ≥70% of the nights monitored. We investigated the long-term beneficial effects of CPAP on sleep qual...