Background Sperm preparation before assisted reproductive techniques is very important for obtaining successful fertilization and pregnancy. During ICSI technique, sperms are selected based on viability and morphology. But this selection did not guarantee integrity of sperm DNA. Therefore, novel sperm selection procedures are introduced for selection of sperm with low DNA damage. One of these p...

Abstract Study question Does the novel strategy in-situ microfluidics (isM) yield comparable ICSI outcomes to control sperm selection methodology density gradient centrifugation (DGC)? Summary answer show that handmade of fluidic walls are as effective DGC achieve fertilization and usable day 5 blastocyst formation rate. What is known already Microfluidics technologies proving their capability ...

In the mature heart, the intercalated disc and costameres provide the cell-cell and cell-matrix junctions respectively. Intercalated disc is situated at the bipolar ends of the cardiomyocytes and the myofibrils are anchored at this structure. The costameres mediate integration with the extracellular matrix that covers individual cardiomyocytes laterally. Costameres are considered as "proteic ma...

The dystrophin-glycoprotein complex (DGC) serves as a link between cytoplasmic actin, the membrane and the extracellular matrix of striated muscle. Genetic defects in genes encoding a subset of DGC proteins result in muscular dystrophy and a secondary decrease in other DGC proteins. Caveolae are dynamic structures that have been implicated in a number of functions including endocytosis, potocyt...

Without the SNF-6 acetylcholine transporter (bottom) mutant muscles fall apart. K im /M ac m ill an they are mutant for various members of the dystrophinglycoprotein complex (DGC), which links intracellular actin to extracellular laminin. But now, Hongkyun Kim, Steven McIntire (University of California, San Francisco, CA), and colleagues suggest that loss of the DGC results in loss of an associ...

The principles and advantages of the dry-gel conversion (DGC) method are described for the synthesis of zeolites Beta and EU-1 with different aluminum and gallium contents in the framework. By modern analytical techniques, the processes occurring during the conversion of a dry gel into zeolite particles were investigated. In the case of the dry-gel synthesis of zeolite [Ga]Beta, XRD indicated a...

The dystrophin-associated glycoprotein complex (DGC) and the α7β1-integrin complex are two independent protein complexes that link the extracellular matrix with the cytoskeleton in muscle cells. These associations stabilize the sarcolemma during force transmission. Loss of either one of these complexes leads to muscular dystrophy. Dystrophin is a major component of the DGC. Its absence results ...

The fourth Daphnia Genomics Consortium Meeting was held from July 7th through July 9th, 2007 at Indiana University (Bloomington, IN, USA). This year’s meeting was entitled The Genome Biology of the Model Crustacean Daphnia and was highlighted by the initial public release of the draft version of the Daphnia pulex genome. In collaboration with the US Department of Energy Joint Genome Institute (...

Aim: The overall goal of this study was to determine what impact the Diabetes Get Checked (DGC) programme had on the practice of nurses, identify those factors that nurses consider contributed to the success or failure of the programme in their work setting, and identify nurses’ suggestions for improved management and outcomes for people with diabetes in the future. Background: Recent research ...

The dystrophin glycoprotein complex (DGC) is a large multisubunit complex located throughout the sarcolemma of striated muscle fibers. This complex is critical for maintaining the structural integrity of muscle fibers during muscle contraction and also provides a scaffold for signaling molecules. Defects in some components of the DGC, such as dystrophin and sarcoglycans, disrupt the complex and...