Under inducing conditions, haploid Saccharomyces cerevisiae perform a dimorphic transition from yeast-form growth on the agar surface to invasive growth, where chains of cells dig into the solid growth medium. Previous work on signaling cascades that promote agar invasion has demonstrated upregulation of FLO11, a cell-surface flocculin involved in cell-cell adhesion. We find that increasing FLO...

Desmoplastic infantile astrocytoma (DIA) is a rare, supratentorial, dural-based, large cystic tumor that usually arises in the first 24 months of life. However, non-infantile cases were also reported in the literature. Desmoplastic infantile astrocytoma and desmoplastic infantile ganglioglioma (DIG) are both classified as grade I astrocytoma by the World Health Organization (WHO). Grossly, DIA/...

We previously developed the direct interaction approximation (DIA) method to estimate the protein-ligand binding free energy (DG). The DIA method estimates the DG value based on the direct van der Waals and electrostatic interaction energies between the protein and the ligand. In the current study, the effect of the entropy of the ligand was introduced with protein dynamic properties by molecul...

PURPOSE Grinding with less stress on 3Y-TZP through proper selection of methods and instruments can lead to a long-term success of prosthesis. The purpose of this study was to compare the phase transformation and physical properties after zirconia surface grinding with 3 different grinding burs. MATERIALS AND METHODS Forty disc-shaped zirconia specimens were fabricated. Each Ten specimens wer...

The diaphanous gene is the founding member of a family of Diaphanous-related formin proteins (DRFs). We identified diaphanous in a screen for genes that are necessary for the normal growth and stabilization of the Drosophila neuromuscular junction (NMJ). Here, we demonstrate that diaphanous mutations perturb synaptic growth at the NMJ. Diaphanous protein is present both presynaptically and post...

The hydrodynamics, viz. the solids circulation patterns and bubble behavior, of a freely bubbling gas-solid fluidized bed has been investigated experimentally using Particle Image Velocimetry (PIV) combined with Digital Image Analysis (DIA). Coupling of these non-invasive measuring techniques allows us to obtain information on both the bubble behavior and emulsion phase circulation patterns sim...

In this paper, we introduce a conceptual tuple-based model for specifi cation of spatial, temporal and semantic relationships among media segments in a multimedia presentation. A multimedia presentation contains various kinds of multimedia objects such as audio, video, images, text media types and so on. The organization of a presentation is a complex task in that the display order of presentat...

The FASiL dialogue manager is described in the context of the commercial deployment of conversational interfaces. A practical dia logue model is presented that uses a list-like structure to manage mixed-initiative dialogue using highly modularised, and independently specified dialogue comp onents.