OBJECTIVE The purpose of this study was to develop a questionnaire that measures patients' perceptions of the impact of diabetic peripheral neuropathy and foot ulcers on their quality of life and to assess the psychometric properties of this instrument in a sample of patients with varying severity and symptomatology of diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS The neuropathy...

AIMS To identify better cells for the treatment of diabetic critical limb ischemia (CLI) and foot ulcer in a pilot trial. METHODS Under ordinary treatment, the limbs of 41 type 2 diabetic patients with bilateral CLI and foot ulcer were injected intramuscularly with bone marrow mesenchymal stem cells (BMMSCs), bone marrow-derived mononuclear cells (BMMNCs), or normal saline (NS). RESULTS The...

The main aim is Secondary Structure Prediction of proteins causing Diabetic Foot Ulcers using Artificial Neural Networks.Protein structure prediction is one of the most important goals pursued by bioinformatics. The knowledge or prediction of secondary structure improves detection and alignment of remote homologs and helps for drug design. The purpose of this study is to identify the Secondary ...

INTRODUCTION: Diabetic foot ulceration is known to be the result of multiple factors, including neuropathy, plantar pressure, shoe fit, and pedal soft tissue thickness. Excessive pressure is recognized to play a role by inducing ischemic change. There is no standardized normal value for pedal soft tissue thickness. In this study, we aimed to investigate the degree of pedal soft tissue atrophy d...

INTRODUCTION Charcot foot is a severe complication to diabetes mellitus and treatment involves several different clinical specialities. Our objective was to describe the current awareness, knowledge and treatment practices of Charcot foot among doctors who handle diabetic foot disorders. METHODS This study is based on a questionnaire survey sent out to healthcare professionals, primarily doct...

Background: The impact of foot ulceration on the psychosocial wellbeing Nigerian diabetic patients has not received enough attention. This study therefore attempted to evaluate effect ulcer quality life adults in a population.
 Methodology: impacts (DFU) (QoL) 104 living with diabetes were assessed using Diabetes Foot Ulcer Scale and their determinants.
 Results: mean QoL score was 42...

Diabetic foot ulcers should be treated to maintain health status, improve quality of life, reduce the number of amputations and lower costs. Many centres that treat diabetic foot ulcers use a multidisciplinary team approach, which comprises medical staff, nurses, podiatrists and an orthotist. At the Manchester Diabetes Centre, larval therapy has been used for several years to debride sloughy di...

In 2007 the IWDGF produced a consensus document on peripheral arterial disease (PAD) in diabetes. In recent years new techniques and technologies have been introduced in treating PAD, which might be relevant for the patient with diabetes and a poorly healing ischemic foot ulcer. The editorial board of International Working Group on the Diabetic Foot (IWDGF) therefore established in 2009 a multi...

BACKGROUND We sought to examine the economic value of specialized lower-extremity medical care by podiatric physicians in the treatment of diabetic foot ulcers by evaluating cost outcomes for patients with diabetic foot ulcer who did and did not receive care from a podiatric physician in the year before the onset of a foot ulcer. METHODS We analyzed the economic value among commercially insur...

AIMS The aim of the study was to explore the prevalence and clinical characteristics of hand ulcer in hospitalized patients with diabetes. METHODS We analysed 17 subjects with hand ulcer among diabetic inpatients, who were admitted to the Diabetic Foot Care Center, Department of Endocrinology and Metabolism at the West China Hospital of Sichuan University from April 2003 to December 2008. R...