Normal and streptozotocin-diabetic rats were fed a low carbohydrate diet or one of two high carbohydrate diets (sucrose or starch-bran). High carbohydrate diets were associated with slightly higher plasma glucose levels in both control and diabetic rats. However, glucose tolerance tests were not altered by the diets in either the control or diabetic rats. Plasma and liver triglyceride values fo...

background & aim: diabetes mellitus is a chronic disease characterized by elevated blood glucose levels and disturbances in carbohydrate, fat and protein metabolism. the objective of the present investigation was to evaluate the therapeutic efficacy of morus alba leaves in an animal model of diabetes. martial & methods: 30 adult male wistar strain rats (200-250 g) were divided randomly...

glycosaminoglycan (gag) has a pivot role in renal function and homeostasis. analysis of gag amount generally serves to determine gag alteration due to diabetes mellitus. critical electrolyte concentration (cec) staining can be an efficacy method to study gag amount changes. based on an experimental study, 20 male rats were randomly divided equally into two experimental and control groups. diabe...

diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. aegle marmelos corr. from rutaceae family, is widely used in iranian folk medicine for the treatment of diabetes mellitus. it decreases blood glucose level by improving glucose tolerance and also has lipid-lowering and antioxidant properties. considering the beneficial antidiabetic potential of a...

This review focuses on the role of reactive oxygen species (ROS) development type 1 and 2 diabetes its treatment with secoisolariciresinol diglucoside (SDG) isolated from flaxseed which is an antioxidant suppresses phosphoenolpyruvate carboxykinase (PEPCK) gene expression, a ratelimiting enzyme in gluconeogenesis liver. Role ROS [diabetic prone Bio Breeding (BBdp) rats streptozotocin-induced di...

objective: diabetes is an important risk factor for cardiovascular events. the great percent of morbidity in patients with diabetes is due to endothelial dysfunction. the present study investigated the effects of hydroalcholic extract of nigella sativa (n. sativa)  on contractile and dilatation response of isolated aorta in streptozotocin (stz)-induced diabetic rat. materials and methods: rats ...

Angiotensin-converting enzyme (ACE) inhibitors appear to correct many of the abnormalities associated with the vascular dysfunction found in diabetic patients. In this respect, quinapril is a unique ACE inhibitor with multiple protective effects. The present study was carried out to investigate the effect of intraperitoneal administration of quinapril on the aortic reactivity of streptozotocin ...

Objective: L-carnitine is associated with an increase in antioxidant enzymes activities and reduction in oxidative damage. The aim of this study was to evaluate the effect of aerobic training and L-carnitine cconsumption on hippocampal oxidative stress and neurogenesis factors in diabetic rats. Materials and Methods: In this experimental study, 45 male wistar rats were divided into six groups ...

The purpose of this study was to determine whether exercise training would prevent the progressive functional decline in pump function of hearts from diabetic rats. Four groups were studied: sedentary control, trained control, sedentary diabetic, and trained diabetic. Trained rats were adapted to the treadmill prior to induction of diabetes in half of the group streptozotocin injected (50 mg/kg...