Cervical cancer is the most frequently observed malignancy during pregnancy. The presence of nodal metastasis is the most important negative predictor factor, and its assessment is crucial in deciding whether the pregnancy can safely continue. To our knowledge, this is the first report of a twin pregnancy complicated by cancer of the uterine cervix that was successfully treated with laparoscopi...

Fetal arrhythmias are diagnosed in 1 to 3% of pregnancies, of which supraventricular tachycardia (SVT) constitutes 10% (Reed, 1989). Sustained fetal SVT with a heart rate more than 220 beats per minute (bpm) can result in congestive heart failure and nonimmune hydrops, which is associated with a poor outcome (Simpson and Sharland, 1998). SVT in twin pregnancy is infrequently reported and poses ...

Abstract Background Vitamin D deficiency is a global public health issue in women and children associated with adverse impacts on child growth, such as rickets. However, prior studies have mainly focused measuring vitamin levels singleton pregnant their offspring, very limited revealed the prevalence of twin offspring. The aim this study was to investigate twin-pregnant neonates. We also explor...

Human cytomegalovirus (CMV) is the most common cause of viral intrauterine infection and fetal damage largely attributable to maternal primary infection. Most cases of congenital CMV infection in twins reported in the literature involved only 1 twin. We assessed the validity of polymerase chain reaction (PCR) and quantitative PCR on amniotic fluid (AF), at 21 to 22 weeks' gestation and at least...

In Brief OBJECTIVE: To evaluate the accuracy and diagnostic value of genome-wide noninvasive prenatal testing (NIPT) for detection fetal aneuploidies in multiple gestations, with a focus on dichorionic–diamniotic twin pregnancies. METHODS: We performed retrospective cohort study including data from pregnant women or higher-order gestation who underwent NIPT at one eight Belgian genetic centers ...

Twin-to-twin transfusion syndrome (TTTS) affects 15% of monochorionic diamniotic (MD) twin pregnancies, and is associated with adverse perinatal outcome. Recently, fetoscopic laser photocoagulation (FLP) has been widely accepted as the most definitive therapy to treat TTTS. N-terminal pro-brain natriuretic peptide (NT-proBNP) is a powerful diagnostic marker of cardiac dysfunction in neonates, a...

OBJECTIVES To determine current trends for different modes of delivery in twin pregnancies, factors affecting the mode of delivery, and associated outcomes. DESIGN Retrospective cohort study. SETTING A public hospital in Hong Kong. PARTICIPANTS All twin pregnancies booked at Kwong Wah Hospital during a 3-year period from 1 April 2006 to 31 March 2009. RESULTS Of 197 sets of twins, 35 (1...