During cotranslational protein translocation, the ribosome associates with a membrane channel, formed by the Sec61 complex, and recruits the translocon-associated protein complex (TRAP). Here we report the structure of a ribosome-channel complex from mammalian endoplasmic reticulum in which the channel has been visualized at 11 A resolution. In this complex, single copies of Sec61 and TRAP asso...

Dieses Papier bereitet die gängige Literatur zum Thema „Divestment“ auf. Über eine lange Zeit konnten viele Firmen, für den Einsatz umweltschädlicher Technologien bekannt waren, davon ausgehen, dass sie nicht über Finanzmarkt sanktioniert werden. Heutzutage scheint Divestment verbreitete Strategie zu sein, um umweltschädliche Unternehmensaktivitäten sanktionieren. Grundlegende theoretische Arbe...

The flickery block of single Ca2+-activated K+ channels that is produced by internally applied Na+ can be relieved by millimolar concentrations of external K+. This effect of K+ on the kinetics of Na+ block was studied by the method of amplitude distribution analysis described in the companion paper (Yellen, G., 1984b, J. Gen. Physiol., 84:157-186). It appears that K+ relieves block by increasi...

We present laser-induced fluorescence velocimetry measurements of the 5d[4]7/2 → 6p[3]5/2 transition for singly-charged xenon (Xe II) at 834.953 nm (vacuum) in the near-field plume of a 6-kW Hall thruster. Axial velocity profiles were obtained at six locations axially along the channel centerline and nine locations radially across the thruster channel at the exit plane. Discharge voltage was ma...

Cyanuric acid hydrolases are of industrial importance because of their use in aquatic recreational facilities to remove cyanuric acid, a stabilizer for the chlorine. Degradation of excess cyanuric acid is necessary to maintain chlorine disinfection in the waters. Cyanuric acid hydrolase opens the cyanuric acid ring hydrolytically and subsequent decarboxylation produces carbon dioxide and biuret...

Transepithelial Cl- secretion in vertebrates is accomplished by a secondary active transport process brought about by the coordinated activity of apical and basolateral transport proteins. The principal basolateral components are the Na+/K(+)-ATPase pump, the Na+/K+/2Cl- cotransporter (symporter) and a K+ channel. The rate-limiting apical component is a cyclic-AMP-stimulated Cl- channel. As pos...

We propose a stringy version of the old inflation scenario which does not require any slowroll inflaton potential and is based on a specific example of string compactification with warped metric. Our set-up admits the presence of anti-D3-branes in the deep infrared region of the metric and a false vacuum state with positive vacuum energy density. The latter is responsible for the accelerated pe...

die direktreduktion von eisenerzen zu eisenschwamm mittels erdgas wird iiberall dort verwendet wo einmal die notwendtigen rohstoffe und besonders der metallurgische koks zu wirtschaftlischen bedingungen fehlen. andereseirs wiederum miissen erdgasrerven in geniigenden mengen und qualitat zu verfugung stehen, urn die direktredution mit gutem wirkungsgrad durchfuhren zu konnen. in dieser arbeit wi...

Recent developments in nanostructured products draw considerable attention to ultrafine grained materials. These materials are normally manufactured by different severe plastic deformation (SPD) methods. In the present study, analytical models and finite element method (FEM) are used to calculate strain imposed to a specimen that was deformed by equal channel angular pressing (ECAP). In additio...

Nach dem kurzen Bericht ueber die Geschichte van Tetanus; haben wir in diesern Artikel ver­sucht,ueber die Epedirniologie, Pathophisiolo­gie,Aethiologie und die Frueh-und Spaet-Symp­ptome von dieser gcfahrlichen Krankheit,die einen Durchschnitt von 35% Mortalitaet hat,zu berichten.  In disern Artikel legen wir vi.ei wert,besoaders ueber die The·.rapie 1md der Prophyla.xe. Unc:I wii' hal)en bed...