We show that dielectrophoresis (DEP) spectroscopy is an effective transduction mechanism for detection of the concentration levels pancreatic cancer biomarkers antigen (CA) 242 and carcinoembryonic (CEA) in serum. noticed a frequency dependence negative DEP force applied by interdigitated electrodes on functionalized polystyrene microspheres (PM) with respect to changes number these antigens bo...

We have designed a dielectrophoresis-based lab-on-chip using MIT Lincoln Labs 0.18 μm 3D integrated circuit technology. Dielectrophoresis is the phenomena where electric fields are used to control the movement of particles in a fluid. The topmost tier of a three chip stack (figure 1) is used to create a microfluidic trench and dielectrophoresis electrode array. During the 3D fabrication process...

We describe methods and results of simulations done for predicting behavior of particles in an aqueous solution under an applied AC electric field on electrodes of rectangular and triangular shapes. Here the two major effects which come into play are Dielectrophoresis and AC electroosmosis. Two simulations have been presented, one for rectangular and one for triangular shaped electrodes. Both t...

ELECTROPHORESISVolume 44, Issue 11-12 p. 878-878 EDITORIAL BOARDFree Access Editorial Board: Electrophoresis 11–12'23 First published: 16 June 2023 https://doi.org/10.1002/elps.202370062AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version art...

Multilayering microelectrode techniques have been developed to construct large-area travelling-wave dielectrophoresis (TWD) separators. Novel electrode designs have enabled arrays with up to 25 000 electrodes to be constructed. The separation capacity of a 1000 electrode (20 mm) array has been demonstrated by separating components of whole blood. The development of sophisticated bio-particle se...

Dielectrophoresis (DEP) has widely been used to probe the dielectric properties of particles, recently including the manipulation and study of colloidal particles. The ability to discriminate between particles collecting on an electrode against those particles in the bulk solution is required for collection rate measurements. In this paper we demonstrate how evanescent imaging methods can be us...

DOI: 10.1002/elps.202200295 The cover picture shows yellow and blue nanoparticles attracted to the electrodes of a microelectrode array designed for dielectrophoresis-based particle collection in high conducting media such as plasma. A protective hydrogel layer forms dome structure over when an electric field is applied. domes likely have insulative effect which intensifies gradient at electrod...