abstract background: the main goals in treating burns are to accelerate tissue renovation and prevent infection. topical antibiotics are used in the treatment of burns, but they can cause side effects. recently, a traditional ointment (olea) has been used in iran in the treatment of burns. this study examines the effect of topical honey ointment in healing of burn patients. materials and method...

Antiarrhythmic effects of intravenous coronary vasodilators (verapamil, diltiazem, bepridil, trimetazidine and nicorandil) were evaluated using two canine ventricular arrhythmia models (halothane-adrenaline arrhythmia and digitalis arrhythmia), and the minimum effective plasma concentrations of the drugs were determined for each arrhythmia model. Verapamil (0.1 mg/kg), diltiazem (0.1 mg/kg), be...

OBJECTIVE This study aimed to show the effects of intra-operative diltiazem infusion on flow in arterial and venous grafts in coronary artery bypass graft surgery. METHODS Hundred fourty patients with a total of 361 grafts [205 (57%) arterial and 156 (43%) venous] underwent isolated coronary surgery. All the grafts were measured by intraoperative transit time flow meter intra-operatively. Gro...

Effects of Ca2+ antagonists, verapamil and diltiazem, on uptake and release of Ca2+ by microsomes of the renal cortex were studied. Verapamil inhibited the ATP-dependent Ca2+ uptake by renal microsomes. Addition of 0.8 mM verapamil was required to produce 50% inhibition of the ATP-dependent CA2+ uptake. Diltiazem also depressed the Ca2+ uptake was not due to an increased permeability for Ca2+, ...

This report describes the use of diltiazem to control circulatory fluctuations during anaesthesia in five patients undergoing resection of a phaeochromocytoma. Diltiazem was administered continuously i.v. before anaesthesia and during surgery until the draining vein from the tumour had been ligated. Arterial pressure and systemic vascular resistance decreased in association with the infusion of...

BACKGROUND Erythrasma is a benign dermatosis that typically occurs on intertriginous skin. PURPOSE We describe a series of nine men with erythrasma that were successfully treated with mupirocin 2% ointment monotherapy. METHODS AND MATERIALS We reviewed PubMed for the following terms: erythrasma, mupirocin, ointment, treatment. We also reviewed papers containing these terms and their referen...

In developing of ointment for topical treatment of colds the structural and mechanical properties of the ointment bases contained isopropyl palmitate, beeswax and solid fat in different concentrations have been studied. Amount of isopropyl palmitate 60% remained constant and the ratio of solid fat and bee wax was varied. In order to study thixotropic properties the curve of kinetics deformation...

In the Present study, methanolic, chloroform and diethyl ether extracts of Adhatoda vasica Plants were evaluated for its wound healing activity in the form of Ointment dosage form in excision wound model in albino rats. The methanolic extract ointment of Adhatoda vasica showed a significant effect in excision wound model as comparable to standard drug and other two extracts of ointment, by calc...