نتایج جستجو برای: dipyridamole

تعداد نتایج: 2097  

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003
Andreas Kjaer Christian Meyer Flemming S Nielsen Hans-Henrik Parving Birger Hesse

UNLABELLED Much evidence suggests endothelial dysfunction to be present in non-insulin-dependent diabetes mellitus (NIDDM) and to be important for the development of myocardial ischemia. Endothelial function in the coronary vessels may be studied in various ways. We compared the effect of cold pressor testing (CPT) with that of dipyridamole, a pharmacologic vasodilator, on coronary blood flow (...

Journal: :medical journal of islamic republic of iran 0
m rezayat from the dept. of pharmacology, school of medicine, tehran university of medical sciences, tehran, islamic republic of iran. m omidi m ramazani m karami h saberi a bakhtiarian

paraquat (pq) is a widely used herbicide. however, a large number of cases of accidental or suicidal poisoning from pq has been reported. membrane damage induced by lipid peroxidation, inactivation of protein or damage to dna by radical formation have been suggested as toxicity mechanisms of pq. in the present work, the effects of atropine, propranolol, procainamide and dipyridamole on pq-induc...

Journal: :Circulation 1994
S D Rosen N G Uren J C Kaski D Tousoulis G J Davies P G Camici

BACKGROUND It remains unclear whether myocardial ischemia due to coronary microvascular dysfunction is the cause of chest pain in syndrome X (chest pain, ischemic-like stress ECG despite angiographically normal coronary arteries). To assess the function of the coronary microcirculation and its relation to pain perception, we measured myocardial blood flow (MBF) and coronary vasodilator reserve ...

Journal: :American journal of physiology. Heart and circulatory physiology 2004
Irina Shuralyova Panteha Tajmir Philip J Bilan Gary Sweeney Imogen R Coe

Inhibition of adenosine reuptake by nucleoside transport inhibitors, such as dipyridamole and dilazep, is proposed to increase extracellular levels of adenosine and thereby potentiate adenosine receptor-dependent pathways that promote cardiovascular health. Thus adenosine can act as a paracrine and/or autocrine hormone, which has been shown to regulate glucose uptake in some cell types. However...

Journal: :Circulation 1994
E D Engelstein B B Lerman V K Somers R F Rea

BACKGROUND Exogenous adenosine has been shown to increase muscle sympathetic nerve activity (MSNA), blood pressure, heart rate, and ventilation in conscious humans, effects attributed to peripheral chemoreceptor activation. METHODS AND RESULTS To determine whether endogenous adenosine has similar effects and whether they are mediated through chemoreceptor activation, we examined the effects o...

2015
Christine Benn Christiansen Jannik Pallisgaard Thomas Alexander Gerds Jonas Bjerring Olesen Mads Emil Jørgensen Anna Karin Numé Nicholas Carlson Søren Lund Kristensen Gunnar Gislason Christian Torp-Pedersen

BACKGROUND In patients with ischemic stroke of non-cardioembolic origin, acetylsalicylic acid, clopidogrel, or a combination of acetylsalicylic acid and dipyridamole are recommended for the prevention of a recurrent stroke. The purpose of this study was to examine the risk of bleeding or recurrent stroke associated with these three treatments. METHODS Patients who were discharged with first-t...

2006
Francesco De Prisco

Myocardial ischemia results in altered left ventricular (LV) diastolic compliance, reflected by an abnormal mitral inflow pattern on Doppler echocardiography. To investigate the relationship of Doppler echocardiography and regional myocardial systolic function during dipyridamole infusion, we evaluated transmitral flow changes detected by pulsed Doppler technique during a high-dose dipyridamole...

Journal: :Molecular pharmacology 2005
Frank Visser Jing Zhang R Taylor Raborn Stephen A Baldwin James D Young Carol E Cass

Human equilibrative nucleoside transporters 1 and 2 (hENT1 and hENT2) differ functionally in that hENT2 generally displays lower affinity for its nucleoside permeants and is less sensitive to inhibition by the coronary vasodilators dilazep and dipyridamole. In previous work, we demonstrated that mutation of residues 33 (Met versus Ile) of hENT1 and hENT2 altered sensitivity to dilazep and dipyr...

2015
Doğangün Yüksel Suna Kıraç Olga Yaylalı Beyza Akdağ Dursun Dursunoğlu

Introduction: We aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected CAD is different from that of intravenous (IV) dipyridamole using Tc-99m MIBI myocardial perfusion gated SPECT. Methods: Eighty-nine patients (17 male, 72 female; 61±10 years) were enrolled in this study. The patients underwent a dipyridamole ...

2016
GIAN BATTISTA DANZI

Objectives. This study sought to investigate the angiographic or intracoronary Doppler variables of stenosis severity that best correlate with the results of dipyridamole echocardiography. Background. Quantitative coronary angiography and intracoronary Doppler flow velocity assessments are the commonly used techniques for the objective identification of significant coronary artery stenosis. Met...

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