This paper studies the disruption management problem of rapid transit rail networks. Besides optimizing the timetable and the rolling stock schedules, we explicitly deal with the effects of the disruption on the passenger demand. We propose a two-step approach that combines an integrated optimization model (for the timetable and rolling stock) with a model for the passengers' behavior. We repor...

Disconnected pancreatic duct syndrome is a serious complication of acute pancreatitis which is defined by a complete discontinuity of the pancreatic duct, such that a viable side of the pancreas remains isolated from the gastrointestinal tract. This pancreatic disruption is infrequently observed in the clinical practice and its diagnostic and therapeutic management are controversial. We present...

Lepidopteran insects use sex pheromones to communicate for mating. Olfactory communication and mate-finding can be prevented by permeating the atmosphere with synthetic pheromone. Pheromone-mediated mating disruption has become a commercially viable pest management technique and is used to control the codling moth, Cydia pomonella, a key insect pest of apple, on 160,000 ha worldwide. The codlin...

Disruption management is one of the most important scheduling problems in the airline industry because of the elevated costs associated, however this is relatively new research area comparing for example with fleet and tail assignment. The major goal to solve this kind of problem is to achieve a feasible solution for the airline company minimizing the several costs involved and within time cons...

Partial ureteropelvic junction disruption as a result of blunt trauma is rare and frequently missed by the initial trauma evaluation. Delays in diagnosis have also been associated with significant morbidity. A high index of suspicion should lead to appropriate investigations, and the management will be determined by the severity of the disruption. We present herein a 24-year-old man who was adm...

BACKGROUND Tracheal disruption secondary to blunt force occurs infrequently. Most individuals suffering such an injury die before arriving at a hospital. Diagnosis for those who do present alive is often delayed, as signs and symptoms typically do not match the severity of injury. OBJECTIVE The objectives of this case report are to present a unique mechanism for tracheal disruption and to dis...

Purpose: The main purpose of this article is to explore the trade-off between ordering policies and disruption risks in a dual-sourcing network under specific (or not) service level constraints, assuming that both supply channels are susceptible to disruption risks. Design/methodology/approach: Stochastic newsvendor models are presented under both the unconstrained and fill rate constraint case...